Acknowledgement
본 연구는 중소벤처기업부와 중소기업기술정보진흥원의 "지역특화산업육성+(R&D, S3370592)" 사업의 지원을 받아 수행된 연구결과임.
References
- G. R. Beecher, "Overview of Dietary Flavonoids: Nomenclature, Occurrence and Intake", Journal of Nutrition, Vol.133, No.10, pp. 3248S-3254S, (2003). https://doi.org/10.1093/jn/133.10.3248S
- K. Nemeth, G. W. Plumb, J.-G. Berrin, N. Juge, R. Jacob, H. Y. Naim, G. Williamson, D. M. Swallow, P. A. Kroon, "Deglycosylation by Small Intestinal Epithelial Cell Β-Glycosidases Is a Critical Step in the Absorption and Metabolism of Dietary Flavonoid Glycosides in Humans", European Journal of Nutrition, Vol.42, No.1, pp. 29-42, (2003). https://doi.org/10.1007/s00394-003-0397-3
- H, Matsumoto, Y. Ikoma, M. Sugiura, M. Yano, Y. Hasegawa, "Identification and Quantification of the Conjugated Metabolites Derived from Orally Administered Hesperidin in Rat Plasma", Journal Of Agriculture and Food Chemistry, Vol.52, No.2, pp. 6653-6659, (2004). https://doi.org/10.1021/jf0491411
- F. Haidari, S. A. Keshavarz, M. R. Rashidi, M. M. Shahi, "Orange Juice and Hesperetin Supplementation to Hyperuricemic Rats Alter Oxidative Stress Markers and Xanthine Oxidoredutase Activity", Journal of Clinical Biochemtry and Nutrition, Vol.45, No.3, pp. 285-291, (2009). https://doi.org/10.3164/jcbn.09-15
- A. Hirata, Y. Murakami, M. Shoji, Y. Kadoma, S. Fujisawa, "Kinetics of Radical-Scavenging Activity of Hesperetin and Hesperidin and their Inhibitory Activity on Cox-2 Expression", Anticancer Research, Vol.25, No.5, pp. 3367-3374, (2005).
- Y. Hao, Z. Wei, Z. Wang, G. Li, Y. Yao, B. Dun, "Biotransformation of Flavonoids Improves Antimicrobial and Anti-Breast Cancer Activities In Vitro", Foods, Vol.10, No.10, 2367, (2021).
- B. Olas, "A Review Of In Vitro Studies of the Anti-Platelet Potential of Citrus Fruit Flavonoids", Food Chemistry And Toxicology, Vol.150, 112090, (2021).
- A. Paredes, M. Aluzuru, J. Mendez, M. Rodriguez-Ortega, "Anti-Sindbis Activity of Flavanones Hesperetin and Naringenin", Biological and Pharmaceutical Bulletin, Vol.26, No.1, pp. 108-109, (2003). https://doi.org/10.1248/bpb.26.108
- K. Pyrzynska, "Hesperidin: A Review on Extraction Methods, Stability and Biological Activities", Nutrients, Vol.14, No.12, 2387, (2022).
- F. J. Cheng, T. K. Huynh, C. S. Yang, D. W. Hu, Y. C. Shen, C. Y. Tu, Y. C. Wu, C. H. Tang, W. C. Huang, Y. Chen, "Hesperidin Is a Potential Inhibitor Against Sars-Cov-2 Infection", Nutrients, Vol.13, No.8, 2800, (2021).
- R. Cao, Y. Zhao, Z. Zhou, X. Zhao, "Enhancement of the Water Solubility and Antioxidant Activity of Hesperidin by Chitooligosaccharide", Journal of the Science of Food and Agriculture, Vol.98, No.6, pp. 2422-2427, (2018). https://doi.org/10.1002/jsfa.8734
- G. M. Sulaiman, H. M. Waheeb, M. S. Jabir, S. H. Khazaal, Y. H. Dewir, Y. Naidoo, "Hesperidin Loaded on Gold Nanoparticles as a Drug Delivery System for a Successful Biocompatible, Anti-Cancer, Anti-Inflammatory and Phagocytosis Inducer Model", Scientific Reports, Vol.10, 9362, (2020).
- K. Slamova, J. Kapesova, K. Valentova, "Sweet flavonoids: Glycosidase-catalyzed Modifications", International Journal of Molecular Sciences, Vol.19, No.7, 2126, (2018).
- M. Yamamoto, A. Suzuki, T. Hase, "Short-term Effects of Glucosyl Hesperidin and Hesperetin on Blood Pressure and Vascular Endothelial Function in Spontaneously Hypertensive Rats", Journal of Nutritional Science and Vitaminology, Vol.54, No.1, pp. 95-98, (2008). https://doi.org/10.3177/jnsv.54.95
- R. M. Martinez, F. A. Pinho-Ribeiro, V. S. Steffen, C. V. Caviglione, J. A. Vignoli, M. M. Baracat, S. R. Georgetti, W. A. Jr. Verri, R. Casagrande, "Hesperidin methyl chalcone inhibits oxidative stress and inflammation in a mouse model of ultraviolet B irradiation-induced skin damage", Journal of Photochemistry and Photobiology B, 148, pp. 145-153, (2015). https://doi.org/10.1016/j.jphotobiol.2015.03.030
- G. Bens, "Sunscreens", Advances in Experimental Medicine and Biology, 810, pp. 429-463, (2014).
- G. Man, T. M. Mauro, Y. Zhai, P. L. Kim, C. Cheung, M. Hupe, D. Crumrine, P. M. Elias, M. Q. Man, "Topical Hesperidin Enhances Epidermal Function in an Aged Murine Model". Journal of Investigative Dermatology, Vo.135, No.4, pp. 1184-1187, (2015). https://doi.org/10.1038/jid.2014.486
- M. Q. Man, B. Yang, P. M. Elias, "Benefits of Hesperidin for Cutaneous Functions", Evidence-Based Complementary and Alternative Medicine, 266307, (2019).
- S. S. Choi, S. H. Lee, K. A. Lee, "A Comparative Study of Hesperetin, Hesperidin and Hesperidin Glucoside: Antioxidant, Anti-Inflammatory, and Antibacterial Activities In Vitro". Antioxidants, Vol11, 1618, (2022).
- S. S. Choi, K. A. Lee, "Antioxidant, anti-inflammatory, and antimicrobial activity of hesperetin and its cyclodextrin inclusion complexes", Journal of the Korean Applied Science and Technology, Vol.40, No.5. 988~1000, (2023).
- T. Mosmann, "Rapid Colorimetric Assay for Cellular Growth and Survival: Application to Proliferation and Cytotoxicity Assays", Journal of Immunological Methods, Vol.65, No.1-2, pp. 55-63, (1983). https://doi.org/10.1016/0022-1759(83)90303-4
- J. Hosoi, E. Abe, T. Suda, T. Kuroki, "Regulation of melanin synthesis of B16 mouse melanoma cells by 1 alpha, 25-dihydroxyvitamin D3 and retinoic acid", Cancer Research, Vol.45, pp. 1474-1478, (1985).
- P. K. Sudheeran, R. Ovadia, O. Galsarker, I. Maoz, N. Sela, D. Maurer, O. Feygenberg, M. Oren Shamir, N. Alkan. "Glycosylated Flavonoids: Fruit's Concealed Antifungal Arsenal', New Phytologist, Vol.225, No.4, pp. 1788-1798, (2020). https://doi.org/10.1111/nph.16251
- S. Kobayashi, S. Tanabe, M. Sugiyama, Y. Konishi, "Transepithelial Transport of Hesperetin and Hesperidin in Intestinal Caco-2 cell Monolayers", Biochimica et Biophysica Acta (BBA) - Biomembranes, Vol.1778, No.1, pp. 33-41, (2008). https://doi.org/10.1016/j.bbamem.2007.08.020
- T. J. Guzik, R. Korbut, T. Adamek-Guzik, "Nitric Oxide and Superoxide in Inflammation and Immune Regulation", Journal of Physiology and Pharmacology, Vol.54, No.4, pp. 469-487, (2003).
- M. Matsumoto, N. Matsukawa, H. Mineo, H. Chiji, H. Hara, "A Soluble Flavonoid-glycoside, AlphaG-rutin, Is Absorbed as Glycosides in the Isolated Gastric and Intestinal Mucosa", Bioscience, Biotechnology, and Biochemistry, Vol.68, No.9, pp. 1929-1934, (2004) https://doi.org/10.1271/bbb.68.1929
- D. Prochazkova, I. Bousova, N. Wilhelmova, "Antioxidant and Prooxidant Properties of Flavonoids", Fitoterapia, Vol.82, No.4, pp. 513-523, (2011). https://doi.org/10.1016/j.fitote.2011.01.018
- J. H. Kim, S. H. Park, E. J. Baek, C. H. Han, N. J. Kang, "Anti-oxidant and Anti-inflammatory Effects of Rutin and its Metabolites", Current Research in Agriculture and Life Sciences, Vol.31, No.3, pp. 165-169, (2013).
- K. Sak, "Cytotoxicity of dietary flavonoids on different human cancer types", Pharmacognosy Reviews, Vol.8, Issue 16, pp. 122-146, (2014). https://doi.org/10.4103/0973-7847.134247
- J. Londono-Londono, V. R. Lima, C. Jaramillo, T. Creczynski-Pasa, "Hesperidin and hesperetin membrane interaction: understanding the role of 7-O-glycoside moiety in flavonoids", Archives of Biochemistry and Biophysics, Vol.499, No.1-2, pp. 6-16, (2010). https://doi.org/10.1016/j.abb.2010.04.023
- J. Xiao, "Dietary flavonoid aglycones and their glycosides: Which show better biological significance?" Critical Reviews in Food Science and Nutrition, Vol.57, No.9, pp. 1874-1905, (2017).
- V. Habauzit, I. Nielsen, A. Gil-Izquierdo, A. Trzeciakiewicz, C. Morand, W. Chee, D. Barron, P. Lebecque, M. J. Davicco, G. Williamson, E. Offord, V. Coxam, M. N. Horcajada, "Increased bioavailability of hesperetin-7-glucoside compared with hesperidin results in more efficient prevention of bone loss in adult ovariectomised rats", British Journal of Nutrition, Vol.102, No.7, pp. 976-984, (2009). https://doi.org/10.1017/S0007114509338830