Journal of Dental Anesthesia and Pain Medicine

The Korean Dental Society of Anesthsiology (대한치과마취과학회)
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Ketamine-propofol (ketofol) in procedural sedation: a narrative review

  • Eun-Ji Choi (Department of Dental Anesthesia and Pain Medicine, School of Dentistry, Dental Research Institute, Dental and Life Science Institute, Pusan National University) ;
  • Cheul-Hong Kim (Department of Dental Anesthesia and Pain Medicine, School of Dentistry, Dental Research Institute, Dental and Life Science Institute, Pusan National University) ;
  • Ji-Young Yoon (Department of Dental Anesthesia and Pain Medicine, School of Dentistry, Dental Research Institute, Dental and Life Science Institute, Pusan National University) ;
  • Eun-Jung Kim (Department of Dental Anesthesia and Pain Medicine, School of Dentistry, Dental Research Institute, Dental and Life Science Institute, Pusan National University)
  • Received : 2023.04.25
  • Accepted : 2023.05.18
  • Published : 2023.06.01
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Abstract

Sedation methods for dental treatment are increasingly explored. Recently, ketofol, which is a combination of ketamine and propofol, has been increasingly used because the advantages and disadvantages of propofol and ketamine complement each other and increase their effectiveness. In this review, we discuss the pharmacology of ketamine and propofol, use of ketofol in various clinical situations, and differences in efficacy between ketofol and other sedatives.

Keywords

Acknowledgement

This study was supported by a 2022 clinical research grant from the Pusan National University Dental Hospital.

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