Korean Journal of Head & Neck Oncology (대한두경부종양학회지)

The Korean Society for Head and Neck Oncology (대한두경부종양학회)
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Efficacy of Picibanil Sclerotherapy in Treatment of Plunging Ranula

몰입성 하마종의 피씨바닐 경화요법 치료 효과

  • Hyun Taek Jung (Department of Otorhinolaryngology, National Health Insurance Service Ilsan Hospital) ;
  • Sangmok Lee (Department of Otorhinolaryngology, National Health Insurance Service Ilsan Hospital) ;
  • Yunbin Nam (Department of Otorhinolaryngology, National Health Insurance Service Ilsan Hospital) ;
  • Jang Won Oh (Department of Otorhinolaryngology, National Health Insurance Service Ilsan Hospital) ;
  • Hyang-Ae Shin (Department of Otorhinolaryngology, National Health Insurance Service Ilsan Hospital) ;
  • Ji-Hoon Kim (Department of Otorhinolaryngology, National Health Insurance Service Ilsan Hospital)
  • 정현택 (국민건강보험 일산병원 이비인후과) ;
  • 이상목 (국민건강보험 일산병원 이비인후과) ;
  • 남윤빈 (국민건강보험 일산병원 이비인후과) ;
  • 오장원 (국민건강보험 일산병원 이비인후과) ;
  • 신향애 (국민건강보험 일산병원 이비인후과) ;
  • 김지훈 (국민건강보험 일산병원 이비인후과)
  • Received : 2022.04.07
  • Accepted : 2023.02.04
  • Published : 2023.05.30
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Abstract

A plunging ranula is a pseudocyst caused by mucus secreted from the sublingual glands, and it is mainly observed on the mouth floor. Nowadays, sclerotherapy using picibanil has been performed instead of invasive surgical treatment, and studies are reporting safe and effective outcomes. In our study, more than 92% of the 25 patients had marked response after picibanil sclerotherapy, and no serious complications were observed. Picibanil sclerotheraphy can be considered as the primary treatment of plunging ranula for patients who refuse surgery under general anaesthesia.

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References

  1. Ogle OE. Excision of sublingual gland. Oral Maxillofac Surg Clin North Am. 2021;33:161-168. https://doi.org/10.1016/j.coms.2020.12.001
  2. Chung YS, Cho Y, Kim BH. Comparison of outcomes of treatment for ranula: a proportion meta-analysis. Br J Oral Maxillofac Surg. 2019;57:620-626. https://doi.org/10.1016/j.bjoms.2019.06.005
  3. Roh JL. Transoral Complete vs Partial Excision of the Sublingual Gland for Plunging Ranula. Otolaryngol Head Neck Surg. 2022;167:479-483. https://doi.org/10.1177/01945998211067500
  4. Kono M, Satomi T, Abukawa H, Hasegawa O, Watanabe M, Chikazu D. Evaluation of OK-432 Injection Therapy as Possible Primary Treatment of Intraoral Ranula. J Oral Maxillofac Surg. 2017;75:336-342. https://doi.org/10.1016/j.joms.2016.08.013
  5. Ogita S, Tsuto T, Nakamura K, Deguchi E, Tokiwa K, Iwai N. OK-432 therapy for lymphangioma in children: why and how does it work? J Pediatr Surg. 1996;31:477-480. https://doi.org/10.1016/S0022-3468(96)90478-9
  6. Ogita S, Tsuto T, Tokiwa K, Takahashi T. Treatment of cystic hygroma in children with special reference to OK-432 therapy. Z Kinderchir. 1987;42:279-281. https://doi.org/10.1055/s-2008-1075602
  7. Patel MR, Deal AM, Shockley WW. Oral and plunging ranulas: What is the most effective treatment? Laryngoscope. 2009;119:1501-1509. https://doi.org/10.1002/lary.20291
  8. Hayashi Y, Torisu M. New approach to management of malignant ascites with streptococcal preparation OK-432. III. OK-432 attracts natural killer cells through a chemotactic factor released from activated neutrophils. Surgery. 1990;107:74-84.
  9. Ohta N, Fukase S, Suzuki Y, Ishida A, Aoyagi M. Treatments of various otolaryngological cystic diseases by OK-4321: its indications and limitations. Laryngoscope. 2010;120:2193-2196. https://doi.org/10.1002/lary.21141
  10. Roh JL, Kim HS. Primary treatment of pediatric plunging ranula with nonsurgical sclerotherapy using OK-432 (Picibanil). Int J Pediatr Otorhinolaryngol. 2008;72:1405-1410. https://doi.org/10.1016/j.ijporl.2008.06.003