한국결정성장학회지 (Journal of the Korean Crystal Growth and Crystal Technology)

  • 제33권3호
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  • Pages.104-109
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  • 2023
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  • 1225-1429(pISSN)
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  • 2234-5078(eISSN)
한국결정성장학회 (The Korea Association of Crystal Growth)
권호 표지
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Electrospun poly(D,L-lactic acid)/gelatin membrane using green solvent for absorbable periodontal tissue regeneration

  • Dayeon Jeong (Department of Biomedical Engineering, Daelim University) ;
  • Juwoong Jang (R&D Center, Renewmedical Co., Ltd.) ;
  • Deuk Yong Lee (Department of Biomedical Engineering, Daelim University)
  • 투고 : 2023.04.25
  • 심사 : 2023.05.03
  • 발행 : 2023.06.30
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초록

Electrospinning was performed using an eco-friendly solvent composed of acetic acid, ethyl acetate and distilled water to investigate the effect of gelatin concentration on mechanical properties and cytotoxicity of absorbable poly(D,L-lactic acid) (PDLLA)/gelatin blend membrane. The tensile stress, strain at break, and WUC of the PDLLA/gelatin (97/3) scaffold at 26 wt% concentration were determined to be 3.9 ± 0.7 MPa, 37 ± 1.3 %, and 273 ± 33 %, respectively. FT-IR results revealed that PDLLA and gelatin were bound only by van der Waals interactions. The cell viability of PDLLA/gelatin membranes containing 0 %, 1 %, 2 %, 3 %, and 4 % gelatin were more than 100 %, which makes all membranes highly suitable as a barrier membrane for absorbable periodontal tissue regeneration due to their marketed physical properties and biocompatibility.

키워드

과제정보

This work was supported by the Technology Development Program (Project No. S3301367), funded by the Ministry of SMEs and Startups (MSS, Korea).

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