Korean Journal of Radiology

The Korean Society of Radiology (대한영상의학회)
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Diagnosing Hepatocellular Carcinoma Using Sonazoid Contrast-Enhanced Ultrasonography: 2023 Guidelines From the Korean Society of Radiology and the Korean Society of Abdominal Radiology

  • Woo Kyoung Jeong (Department of Radiology and Center for Imaging Science, Samsung Medical Center, Sungkyunkwan University School of Medicine) ;
  • Hyo-Jin Kang (Department of Radiology and Research Institute of Radiological Science, Seoul National University Hospital, Seoul National University College of Medicine) ;
  • Sang Hyun Choi (Department of Radiology and Research Institute of Radiology, Asan Medical Center, University of Ulsan College of Medicine) ;
  • Mi-Suk Park (Department of Radiology and Research Institute of Radiological Science, Severance Hospital, Yonsei University College of Medicine) ;
  • Mi Hye Yu (Department of Radiology, Konkuk University Hospital, Konkuk University College of Medicine) ;
  • Bohyun Kim (Department of Radiology, Seoul St. Mary Hospital, College of Medicine, The Catholic University of Korea) ;
  • Myung-Won You (Department of Radiology, Kyung Hee University Hospital, Kyung Hee University College of Medicine) ;
  • Sanghyeok Lim (Department of Radiology, Soonchunhyang University Bucheon Hospital, Soonchunhyang University College of Medicine) ;
  • Young Seo Cho (Department of Radiology, Hanyang University Guri Hospital, Hanyang University College of Medicine) ;
  • Min Woo Lee (Department of Radiology and Center for Imaging Science, Samsung Medical Center, Sungkyunkwan University School of Medicine) ;
  • Jeong Ah Hwang (Department of Radiology and Center for Imaging Science, Samsung Medical Center, Sungkyunkwan University School of Medicine) ;
  • Jae Young Lee (Department of Radiology and Research Institute of Radiological Science, Seoul National University Hospital, Seoul National University College of Medicine) ;
  • Jung Hoon Kim (Department of Radiology and Research Institute of Radiological Science, Seoul National University Hospital, Seoul National University College of Medicine) ;
  • Ijin Joo (Department of Radiology and Research Institute of Radiological Science, Seoul National University Hospital, Seoul National University College of Medicine) ;
  • Jae Seok Bae (Department of Radiology and Research Institute of Radiological Science, Seoul National University Hospital, Seoul National University College of Medicine) ;
  • So Yeon Kim (Department of Radiology and Research Institute of Radiology, Asan Medical Center, University of Ulsan College of Medicine) ;
  • Yong Eun Chung (Department of Radiology and Research Institute of Radiological Science, Severance Hospital, Yonsei University College of Medicine) ;
  • Dong Hwan Kim (Department of Radiology, Seoul St. Mary Hospital, College of Medicine, The Catholic University of Korea) ;
  • Jeong Min Lee (Department of Radiology and Research Institute of Radiological Science, Seoul National University Hospital, Seoul National University College of Medicine)
  • Received : 2023.04.07
  • Accepted : 2023.04.11
  • Published : 2023.06.01
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Abstract

Sonazoid, a second-generation ultrasound contrast agent, was introduced for the diagnosis of hepatic nodules. To clarify the issues with Sonazoid contrast-enhanced ultrasonography for the diagnosis of hepatocellular carcinoma (HCC), the Korean Society of Radiology and Korean Society of Abdominal Radiology collaborated on the guidelines. The guidelines are de novo, evidence-based, and selected using an electronic voting system for consensus. These include imaging protocols, diagnostic criteria for HCC, diagnostic value for lesions that are inconclusive on other imaging results, differentiation from non-HCC malignancies, surveillance of HCC, and treatment response after locoregional and systemic treatment for HCC.

Keywords

Acknowledgement

The authors would like to thank Dr. Mi Young Choi (National Evidence-based Healthcare Collaborating Agency, Korea), Chang Hee Cho (The Korean Society of Radiology, Korea) and Euisoo Shin (University of Ulsan College of Medicine, Asan Medical Library, Korea) for consulting on the evidence search and guideline development process.

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