과제정보
This work was supported by the Research Program 2020 and 2021 of the Korean Society of Ginseng.
참고문헌
- Hu SY. The genusPanax (ginseng) in Chinese medicine. Econ Bot 1976;30:11-28. https://doi.org/10.1007/BF02866780
- Mahady GB, Gyllenhall C, Fong HH, Farnsworth NR. Ginsengs: a review of safety and efficacy. Nutr Clin Care 2000;3:90-101. https://doi.org/10.1046/j.1523-5408.2000.00020.x
- Qi LW, Wang CZ, Yuan CS. Isolation and analysis of ginseng: advances and challenges. Nat Prod Rep 2011;28(3):467-95. https://doi.org/10.1039/c0np00057d
- Kang S, Min H. Ginseng, the 'immunity boost': the effects of Panax ginseng on immune system. J Ginseng Res 2012;36(4):354-68. https://doi.org/10.5142/jgr.2012.36.4.354
- Choi HI, Waminal NE, Park HM, Kim NH, Choi BS, Park M, et al. Major repeat components covering one-third of the ginseng (Panax ginseng C.A. Meyer) genome and evidence for allotetraploidy. Plant J 2014;77(6):906-16. https://doi.org/10.1111/tpj.12441
- Robertson GP, Vitousek PM. Nitrogen in agriculture: balancing the cost of an essential resource. Annu Rev Environ Resour 2009;34:97-125. https://doi.org/10.1146/annurev.environ.032108.105046
- Fredes I, Moreno S, Diaz FP, Gutierrez RA. Nitrate signaling and the control of Arabidopsis growth and development. Curr Opin Plant Biol 2019;47:112-8. https://doi.org/10.1016/j.pbi.2018.10.004
- Wang G-L, Que F, Xu Z, Wang F, Xiong A. Exogenous gibberellin altered morphology, anatomic and transcriptional regulatory networks of hormones in carrot root and shoot. BMC Plant Biol 2015;15:290.
- Zhao LF, Liu F, Crawford NM, Wang Y. Molecular regulation of nitrate responses in plants. Int J Mol Sci 2018;19(7).
- Zhang H, Forde BG. An Arabidopsis MADS box gene that controls nutrient-induced changes in root architecture. Science 1998;279:407-9. https://doi.org/10.1126/science.279.5349.407
- Lima JE, Kojima S, Takahashi H, von Wiren N. Ammonium triggers lateral root branching in Arabidopsis in an AMMONIUM transporter1;3-dependent manner. Plant Cell 2010;22(11):3621-33. https://doi.org/10.1105/tpc.110.076216
- Vega A, O'Brien JA, Gutierrez RA. Nitrate and hormonal signaling crosstalk for plant growth and development. Curr Opin Plant Biol 2019;52:155-63. https://doi.org/10.1016/j.pbi.2019.10.001
- Lam HM, Coschigano KT, Oliveira IC, MeloOliveira R, Coruzzi GM. The molecular-genetics of nitrogen assimilation into amino acids in higher plants. Annu Rev Plant Physiol 1996;47:569-93. https://doi.org/10.1146/annurev.arplant.47.1.569
- Foyer CH, Noctor G, Hodges M. Respiration and nitrogen assimilation: targeting mitochondria-associated metabolism as a means to enhance nitrogen use efficiency. J Exp Bot 2011;62(4):1467-82. https://doi.org/10.1093/jxb/erq453
- Hong CP, Kim J, Lee J, Yoo SI, Bae W, Geem KR, et al. Gibberellin signaling promotes the secondary growth of storage roots in Panax ginseng. Int J Mol Sci 2021;22(16).
- Bjorklund S, Antti H, Uddestrand I, Moritz T, Sundberg B. Cross-talk between gibberellin and auxin in development of Populus wood: gibberellin stimulates polar auxin transport and has a common transcriptome with auxin. Plant J 2007;52(3):499-511. https://doi.org/10.1111/j.1365-313X.2007.03250.x
- Matsumoto-Kitano M, Kusumoto T, Tarkowski P, Kinoshita-Tsujimura K, Vaclavikova K, Miyawaki K, et al. Cytokinins are central regulators of cambial activity. P Natl Acad Sci USA 2008;105(50):20027-31. https://doi.org/10.1073/pnas.0805619105
- Agusti J, Herold S, Schwarz M, Sanchez P, Ljung K, Dun EA, et al. Strigolactone signaling is required for auxin-dependent stimulation of secondary growth in plants. P Natl Acad Sci USA 2011;108(50):20242-7. https://doi.org/10.1073/pnas.1111902108
- Mauriat M, Moritz T. Analyses of GA20ox- and GID1-over-expressing aspen suggest that gibberellins play two distinct roles in wood formation. Plant J 2009;58(6):989-1003. https://doi.org/10.1111/j.1365-313X.2009.03836.x
- Denis E, Kbiri N, Mary V, Claisse G, Silva NCE, Kreis M, et al. WOX14 promotes bioactive gibberellin synthesis and vascular cell differentiation in Arabidopsis. Plant J 2017;90(3):560-72. https://doi.org/10.1111/tpj.13513
- Ristova D, Carre C, Pervent M, Medici A, Kim GJ, Scalia D, et al. Combinatorial interaction network of transcriptomic and phenotypic responses to nitrogen and hormones in the Arabidopsis thaliana root. Sci Signal 2016;9(451).
- Vidal EA, Araus V, Lu C, Parry G, Green PJ, Coruzzi GM, et al. Nitrate-responsive miR 393/AFB3 regulatory module controls root system architecture in Arabidopsis thaliana. P Natl Acad Sci USA 2010;107(9):4477-82. https://doi.org/10.1073/pnas.0909571107
- Chen XB, Yao QF, Gao XH, Jiang CF, Harberd NP, Fu XD. Shoot-to-Root mobile transcription factor HY5 coordinates plant carbon and nitrogen acquisition. Curr Biol 2016;26(5):640-6. https://doi.org/10.1016/j.cub.2015.12.066
- Cluis CP, Mouchel CF, Hardtke CS. The Arabidopsis transcription factor HY5 integrates light and hormone signaling pathways. Plant J 2004;38(2):332-47. https://doi.org/10.1111/j.1365-313X.2004.02052.x
- Schmieder R, Edwards R. Quality control and preprocessing of metagenomic datasets. Bioinformatics 2011;27(6):863-4. https://doi.org/10.1093/bioinformatics/btr026
- Langmead B, Salzberg SL. Fast gapped-read alignment with Bowtie 2. Nat Methods 2012;9(4). 357-U54.
- Li B, Dewey CN. RSEM: accurate transcript quantification from RNA-Seq data with or without a reference genome. BMC Bioinf 2011;12.
- Robinson MD, McCarthy DJ, Smyth GK. edgeR: a Bioconductor package for differential expression analysis of digital gene expression data. Bioinformatics 2010;26(1):139-40. https://doi.org/10.1093/bioinformatics/btp616
- Haas BJ, Papanicolaou A, Yassour M, Grabherr M. Blood PD, Bowden J, et al. De novo transcript sequence reconstruction from RNA-seq using the Trinity platform for reference generation and analysis. Nat Protoc 2013;8(8):1494-512. https://doi.org/10.1038/nprot.2013.084
- Huang DW, Sherman BT, Lempicki RA. Systematic and integrative analysis of large gene lists using DAVID bioinformatics resources. Nat Protoc 2009;4(1):44-57. https://doi.org/10.1038/nprot.2008.211
- Huang DW, Sherman BT, Lempicki RA. Bioinformatics enrichment tools: paths toward the comprehensive functional analysis of large gene lists. Nucleic Acids Res 2009;37(1):1-13. https://doi.org/10.1093/nar/gkn923
- Subramanian A, Tamayo P, Mootha VK, Mukherjee S, Ebert BL, Gillette MA, et al. Gene set enrichment analysis: a knowledge-based approach for interpreting genome-wide expression profiles. P Natl Acad Sci USA 2005;102(43):15545-50. https://doi.org/10.1073/pnas.0506580102
- Shannon P, Markiel A, Ozier O, Baliga NS, Wang JT, Ramage D, et al. Cytoscape: a software environment for integrated models of biomolecular interaction networks. Genome Res 2003;13(11):2498-504. https://doi.org/10.1101/gr.1239303
- Montojo J, Zuberi K, Rodriguez H, Kazi F, Wright G, Donaldson SL, et al. GeneMANIA Cytoscape plugin: fast gene function predictions on the desktop. Bioinformatics 2010;26(22):2927-8. https://doi.org/10.1093/bioinformatics/btq562
- Wickham H. ggplot2: elegant graphics for data analysis. Springer-Verlag New York. ISBN 978-3-319-24277-4.
- Smetana O, Makila R, Lyu M, Amiryousefi A, Rodriguez FS, Wu MF, et al. High levels of auxin signalling define the stem-cell organizer of the vascular cambium. Nature 2019;565(7740):485-+.
- Tian HY, Lv BS, Ding TT, Bai MY, Ding ZJ. Auxin-BR interaction regulates plant growth and development. Front Plant Sci 2018;8.
- Hwang H, Lee HY, Ryu H, Cho H. Functional characterization of BRASSINAZOLE-RESISTANT 1 in Panax ginseng (PgBZR1) and brassinosteroid response during storage root formation. Int J Mol Sci 2020;21(24).
- Zhang J, Eswaran G, Alonso-Serra J, Kucukoglu M, Xiang JL, Yang WB, et al. Transcriptional regulatory framework for vascular cambium development in Arabidopsis roots. Native Plants 2019;5(10):1033-42. https://doi.org/10.1038/s41477-019-0522-9
- Lee J, Kim H, Park SG, Hwang H, Yoo SI, Bae W, Kim E, Kim J, Lee HY, Heo TY, Kang KK, Lee Y, Hong CP, Cho H, Ryu H. Brassinosteroid-BZR1/2-WAT1 module determines the high level of auxin signalling in vascular cambium during wood formation. New Phytol 2021 May;230(4):1503-16. https://doi.org/10.1111/nph.17265.
- Love J, Bjorklund S, Vahala J, Hertzberg M, Kangasjarvi J, Sundberg B. Ethylene is an endogenous stimulator of cell division in the cambial meristem of Populus. P Natl Acad Sci USA 2009;106(14):5984-9. https://doi.org/10.1073/pnas.0811660106
- Wang YY, Cheng YH, Chen KE, Tsay YF. Nitrate transport, signaling, and use efficiency. Annu Rev Plant Biol 2018;69:85-122. https://doi.org/10.1146/annurev-arplant-042817-040056
- Nieminen K, Immanen J, Laxell M, Kauppinen L, Tarkowski P, Dolezal K, et al. Cytokinin signaling regulates cambial development in poplar. P Natl Acad Sci USA 2008;105(50):20032-7. https://doi.org/10.1073/pnas.0805617106
- Liu JX, An X, Cheng L, Chen FJ, Bao JA, Yuan LX, et al. Auxin transport in maize roots in response to localized nitrate supply. Ann Bot-London 2010;106(6):1019-26. https://doi.org/10.1093/aob/mcq202
- Krouk G, Lacombe B, Bielach A, Perrine-Walker F, Malinska K, Mounier E, et al. Nitrate-regulated auxin transport by NRT1.1 defines a mechanism for nutrient sensing in plants. Dev Cell 2010;18(6):927-37. https://doi.org/10.1016/j.devcel.2010.05.008
- Kang A, Zhang N, Xun W, Dong X, Xiao M, Liu Z, et al. Nitrogen fertilization modulates beneficial rhizosphere interactions through signaling effect of nitric oxide. Plant Physiol 2022;188(2):1129-40. https://doi.org/10.1093/plphys/kiab555.