Animal Bioscience

Asian Australasian Association of Animal Production Societies (아세아태평양축산학회)
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Effects of peripartal glucose precursor supplementation on lactation performance and metabolic health of primiparous and multiparous dairy cows

  • Muhammad Uzair Akhtar (Department of Animal Nutrition, University of Veterinary & Animal Sciences) ;
  • Hifzulrahman (Department of Livestock Production, University of Veterinary & Animal Sciences) ;
  • Talat Naseer Pasha (University of Education) ;
  • Muhammad Avais (Department of Veterinary Medicine, University of Veterinary & Animal Sciences) ;
  • Nauman Khan (Pakistan Holstein Pvt. Ltd.) ;
  • Ghazanfar Ali Chishti (Department of Animal Nutrition, University of Veterinary & Animal Sciences) ;
  • Mubashar Ali (Department of Animal Nutrition, University of Veterinary & Animal Sciences) ;
  • Muhammad Imran (Department of Animal Nutrition, KBCMA College of Veterinary and Animal Sciences (Sub-campus University of Veterinary and Animal Sciences)) ;
  • Muhammad Naeem Tahir (University College of Veterinary and Animal Sciences, the Islamia University of Bahawalpur) ;
  • Muhammad Naveed-ul-Haque (Department of Animal Nutrition, University of Veterinary & Animal Sciences)
  • Received : 2022.06.01
  • Accepted : 2022.10.30
  • Published : 2023.06.01
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Abstract

Objective: Hyperketonemia remains a major metabolic issue of serious milk production and a major health concern in early lactation cows. Oral supplementation of glucose precursors (GP) can be used to prevent hyperketonemia in dairy cows. The objective of this study was to compare the beneficial effects of orally supplementing a mixture of GP on metabolic health indicators and milk production status of primiparous (PP) and multiparous (MP) dairy cows. Methods: Twenty-eight Holstein cows were blocked by expected date of parturition, previous lactation yield, and parity. The cows were randomly allocated to one of the four treatment groups (n = 7 cows/group) based on their parity and GP supplementation: i) PP cows fed basal diet only (PP-CON), ii) PP cows with oral supplementation of GP (PP-GP), iii) MP cows fed basal diet only (MP-CON), and iv) MP cows with oral supplementation of GP (MP-GP). Glucose precursor (glycoline liquid) was orally drenched (300 mL/d) in GP cows from 7 days prepartum through 7 days postpartum. Other than GP supplementation, all cows were fed similar pre- and postpartum basal diets. Results: In both pre- and postpartum periods, serum glucose concentration was increased, whereas β-hydroxybutyrate and free fatty acids were decreased in GP cows compared with the CON cows. Milk yield and milk components were statistically not different between GP and CON cows over the first 9 week of lactation. The yield of actual milk, energy-corrected milk, 63-days cumulative milk, colostrum yield, and calf birth weight remained higher in MP cows compared with PP cows. Conclusion: Oral drenching of GP around calving can be recommended to successfully improve the metabolic health and reduce the negative effects of hyperketonemia not only in MP but also in PP dairy cows.

Keywords

Acknowledgement

The authors are sincerely thankful to Shoaib Siddiqui and Asif Subhan from Pakistan Holstein Dairy Farm (Pvt. Ltd.), Risalpur, KPK, and their farm staff, especially M. Wasif, Abdul-Jabbar, Mukhtar Abbasi, Abdullah Khan, Kashif, Dilawar, M. Ali, and Zeeshan for their invaluable assistance in data collection and animal care during the experiment. The authors are grateful to Tariq A. Nawaz and Mirza M. Afzal from Ghazi Brothers, Lahore for donating Glycoline for this study. We also thank Shabbir Hussain, Department of Biochemistry, University of Health Sciences, Lahore for the analysis of serum samples. The assistance of Sajid and Sagheer (Department of Animal Nutrition, University of Veterinary and Animal Sciences, Lahore) during the analysis of feedstuffs is also appreciated.

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