Archives of Plastic Surgery

  • 제50권1호
  • /
  • Pages.106-115
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  • 2023
  • /
  • 2234-6163(pISSN)
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  • 2234-6171(eISSN)
대한성형외과학회 (Korean Society of Plastic and Reconstructive Surgeons)
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Is "Initial Size of the Graft the Real Culprit behind Primary Contraction of Full-Thickness Skin Graft"?-A Cross-Sectional Study

  • Madhubari Vathulya (Department of Burns and Plastic Surgery, All India Institute of Medical Sciences) ;
  • Shalinee Rao (Department of Pathology, All India Institute of Medical Sciences) ;
  • Akanksha Malik (Department of Pathology, All India Institute of Medical Sciences) ;
  • Smita Sinha (Department of Community and Family Medicine, All India Institute of Medical Sciences) ;
  • Nikhilesh Kumar (Department of Burns and Plastic Surgery, All India Institute of Medical Sciences) ;
  • Akshay Kapoor (Department of Burns and Plastic Surgery, All India Institute of Medical Sciences) ;
  • Yogesh Bahurupi (Department of Community and Family Medicine, All India Institute of Medical Sciences)
  • 투고 : 2021.11.12
  • 심사 : 2022.03.31
  • 발행 : 2023.01.15
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초록

Background Primary contraction of full-thickness graft has been traditionally quoted to be 40%. There are lacunae in literature to elaborate on the factors influencing it ever since. Methods About 75 subjects who underwent full-thickness grafting procedures to resurface small defects were included in the study. The initial and final graft dimensions after primary contraction were traced on X-ray templates and the percentage of contraction was evaluated using the graphical method. This was further correlated with age, collagen, elastic matrix metalloproteinases-1 (MMP-1) and -2 content along with dermal thickness of the skin specimen sent from the graft. Results The primary contraction of the graft had a very significant correlation only with the initial size of graft harvested with a linear regression of 33.3% and a Spearman's correlation of 0.587 significant at a p-value of 0.001. Conclusion This study though preliminary tries to highlight an important factor that primary contraction of grafts is a physical phenomenon independent of its contents like collagen, elastin, or MMP-1 and -2 or age and dependent on its initial size of harvest instead.

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과제정보

The project has been funded by an intramural grant: IM/RC108/2016/33.

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