DOI QR코드

DOI QR Code

액와부 부유방에 발생한 과립 세포 종양: 증례 보고

Granular Cell Tumor of the Axillary Accessory Breast: A Case Report

  • 정윤주 (양산부산대학교병원 외과) ;
  • 남경진 (양산부산대학교병원 영상의학과) ;
  • 추기석 (양산부산대학교병원 영상의학과) ;
  • 이계영 (양산부산대학교병원 영상의학과)
  • Youn Joo Jung (Department of Surgery, Pusan National University Yangsan Hospital) ;
  • Kyung Jin Nam (Department of Radiology, Pusan National University Yangsan Hospital) ;
  • Ki Seok Choo (Department of Radiology, Pusan National University Yangsan Hospital) ;
  • Kyeyoung Lee (Department of Radiology, Pusan National University Yangsan Hospital)
  • 투고 : 2022.09.22
  • 심사 : 2022.12.13
  • 발행 : 2023.01.01

초록

과립 세포 종양은 신체의 모든 부위에서 발생할 수 있으나, 특히 두경부에서 주로 발생하는 드문 양성 연부 종양이며, 이 중 5%-8%가 유방에서 발생한다. 저자들은 드문 부위인 액와부 부유방에 발생한 과립 세포 종양 1예를 보고하고자 한다. 50세 여자에게 2개월 전부터 좌측 액와부에 만져지는 종괴가 있었다. 이학적 검사, 유방 촬영술 및 초음파 소견에서 유방의 악성 종양을 먼저 생각하였다. 조직 검사에서 양성 과립 세포 종양으로 진단되었으며 이후 광범위 국소 절제술을 시행하였다. 환자는 수술 후 2년의 추적 관찰 기간 동안 재발하지 않았다. 대부분의 과립 세포 종양은 양성이지만, 재발의 가능성 때문에 종양의 광범위한 완전 절제와 추적 관찰이 필요하다. 영상의학과 의사는 불필요한 치료를 막기 위해 유방 및 액와부 병변의 감별 진단으로 과립 세포 종양의 특징에 대해 알고 있어야 한다.

Granular cell tumors (GCTs) are rare benign soft tissue tumors that can occur throughout the body, particularly the head and neck; only 5%-8% of GCTs occur in the breast. We report a case of a GCT of the axillary accessory breast, which is a rare location of this tumor. A 50-year-old woman had a 2-month history of a palpable mass in the left axilla. Physical examination, as well as mammographic and ultrasonographic findings suggested a breast malignancy. Histopathological examination showed a benign GCT, and wide local excision was performed. The patient has remained disease-free over 2 years postoperatively. Although most GCTs are benign, wide complete resection of the tumor and follow-up are required considering the possibility of recurrence. The radiologist should know the characteristics of GCTs as a differential diagnosis of breast and axillary lesions to prevent unnecessary treatment.

키워드

과제정보

This study was supported by a 2021 research grant from Pusan National University Yangsan Hospital (2021-84).

참고문헌

  1. Pergel A, Yucel AF, Karaca AS, Aydin I, Sahin DA, Demirbag N. A therapeutic and diagnostic dilemma: granular cell tumor of the breast. Case Rep Med 2011;2011:972168 
  2. Gogas J, Markopoulos C, Kouskos E, Gogas H, Mantas D, Antonopoulou Z, et al. Granular cell tumor of the breast: a rare lesion resembling breast cancer. Eur J Gynaecol Oncol 2002;23:333-334 
  3. Yang WT, Edeiken-Monroe B, Sneige N, Fornage BD. Sonographic and mammographic appearances of granular cell tumors of the breast with pathological correlation. J Clin Ultrasound 2006;34:153-160  https://doi.org/10.1002/jcu.20227
  4. Adeniran A, Al-Ahmadie H, Mahoney MC, Robinson-Smith TM. Granular cell tumor of the breast: a series of 17 cases and review of the literature. Breast J 2004;10:528-531  https://doi.org/10.1111/j.1075-122X.2004.21525.x
  5. Liu H, Tao M, Ding H, Zhang P. Ultrasonographic manifestations of a rare granular cell tumor of the accessory breast: a case report. Medicine (Baltimore) 2018;97:e9462 
  6. Olivier L, Naraynsingh V, Hassranah D, Cassim C. Abrikossoff tumor clinically mimicking carcinoma in accessory axillary breast tissue. Cureus 2022;14:e21733 
  7. Scaranelo AM, Bukhanov K, Crystal P, Mulligan AM, O'Malley FP. Granular cell tumour of the breast: MRI findings and review of the literature. Br J Radiol 2007;80:970-974  https://doi.org/10.1259/bjr/95130566
  8. Abreu N, Filipe J, Andre S, Marques JC. Granular cell tumor of the breast: correlations between imaging and pathology findings. Radiol Bras 2020;53:105-111  https://doi.org/10.1590/0100-3984.2019.0056
  9. Brown AC, Audisio RA, Regitnig P. Granular cell tumour of the breast. Surg Oncol 2011;20:97-105  https://doi.org/10.1016/j.suronc.2009.12.001
  10. Heinzerling NP, Koehler SM, Szabo S, Wagner AJ. Pediatric granular cell tumor of the breast: a case report and review of the literature. Case Rep Surg 2015;2015:568940