대한두경부종양학회지 (Korean Journal of Head & Neck Oncology)

  • 제39권2호
  • /
  • Pages.45-48
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  • 2023
  • /
  • 1229-5183(pISSN)
  • /
  • 2586-2553(eISSN)
대한두경부종양학회 (The Korean Society for Head and Neck Oncology)
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제1형 신경섬유종증, 신경섬유종, 악성 말초신경초종

A Case of Early Malignant Change from Neurofibroma to Malignant Peripheral Nerve Sheath Tumor

  • 강푸름 (고신대학교복음병원 이비인후-두경부외과학교실) ;
  • 김영준 (고신대학교복음병원 이비인후-두경부외과학교실) ;
  • 오선주 (고신대학교복음병원 병리과교실) ;
  • 이형신 (고신대학교복음병원 이비인후-두경부외과학교실)
  • Poo Reum Kang (Department of Otolaryngology, Head and Neck Surgery, Kosin University College of Medicine) ;
  • Yeong Joon Kim (Department of Otolaryngology, Head and Neck Surgery, Kosin University College of Medicine) ;
  • Sun Ju Oh (Department of Pathology, Kosin University College of Medicine) ;
  • Hyoung Shin Lee (Department of Otolaryngology, Head and Neck Surgery, Kosin University College of Medicine)
  • 투고 : 2023.08.21
  • 심사 : 2023.09.27
  • 발행 : 2023.11.30
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초록

Malignant peripheral nerve sheath tumor (MPNST) is one of the soft tissue sarcoma believed to originate from neural crest cells. The patients with neurofibromatosis type I (NF1) have about 8-13% of the lifetime risk of the malignant transformation. Neurofibroma on patients with NF1 can be surgically resected and has good prognosis if approach to the tumor is possible. We experienced a case of a 50-year-old woman with NF who had incompletely resected neurofibroma, which presented a rapid malignant transformation to MPNST, 3 months after the first surgery. We reported this case with a brief review of literature.

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참고문헌

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