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노인 두경부암 환자의 생존에 있어 노쇠의 의의

Frailty in Geriatric Patients with Head and Neck Cancer and its Implication in Survivorship

  • 권민수 (울산대학교 의과대학 서울아산병원 이비인후과-두경부외과)
  • Minsu Kwon (Department of Otolaryngology-Head and Neck Surgery, Asan Medical Center, University of Ulsan College of Medicine)
  • 투고 : 2023.11.15
  • 심사 : 2023.11.25
  • 발행 : 2023.11.30

초록

The aging population, particularly those aged 65 and above, is on the rise, with projections indicating a substantial increase in the elderly demographic. This demographic shift brings challenges in managing age-related diseases, including head and neck cancers (HNCs). Frailty, often characterized by physiological decline and vulnerability to stressors, is a crucial factor affecting treatment outcomes of elderly cancer patients. Accordingly, the significance of assessing frailty in elderly HNC patients before their treatment should be emphasized, but current frailty assessment tools may not fully capture the unique challenges faced by HNC patients. Specific indicators, including respiratory and swallowing functions, are proposed for a more tailored assessment. This comprehensive review explores the impact of frailty on various treatment modalities, including surgery, radiation, and chemotherapy, highlighting the need for personalized interventions. Furthermore, it suggests avenues for future research to enhance frailty assessment tools and investigate interventions aimed at improving treatment outcomes in elderly HNC patients.

키워드

과제정보

This work is supported by the National Research Foundation of Korea (NRF) grant funded by the Ministry of Science and ICT (RS-2023-00208625) of Korea.

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