한국임상수의학회지 (Journal of Veterinary Clinics)

  • 제40권1호
  • /
  • Pages.78-82
  • /
  • 2023
  • /
  • 1598-298X(pISSN)
  • /
  • 2384-0749(eISSN)
한국임상수의학회 (The Korean Society of Veterinary Clinics)
권호 표지
DOI QR코드

DOI QR Code

Bacterial Sepsis Associated with a Captive State Caused by Edwardsiella tarda in a Eurasian Brown Bear (Ursus arctos arctos)

  • Min-Goo Seo (College of Veterinary Medicine, Kyungpook National University) ;
  • Kyung-Yeon Eo (College of Healthcare and Biotechnology, Semyung University) ;
  • Dongmi Kwak (College of Veterinary Medicine, Kyungpook National University) ;
  • Kyoo-Tae Kim (College of Veterinary Medicine, Kyungpook National University)
  • 투고 : 2022.11.08
  • 심사 : 2023.01.16
  • 발행 : 2023.02.28
PDF 다운로드
⟨ 이전 논문 다음 논문 ⟩

초록

Edwardsiella (E) tarda belongs to the Enterobacteriaceae family and is a motile, gram-negative, rod-shaped, facultative anaerobe regarded as an opportunistic and food-borne pathogen in animals and humans. A 21-year-old male Eurasian brown bear (Ursus arctos arctos) died suddenly without any preliminary signs. Necropsy performed according to standard protocol revealed swollen abdomen with hemorrhagic congestions of the gastroenteric organs, ascites, and hemorrhagic exudates around the mouth. The liver showed discoloration, along with a severely swollen and multiple hemorrhages of the spleen, an elongated gallbladder, and a congested cortex and medullar lesion of kidneys. The stomach contained semi-liquid exudates and undigested chicken exuding a decayed odor. The stomach membranes were dark-gray in color with several cysts in the fundus lesions. Rod-shaped bacteria were found in the major organs by Giemsa staining, identified as E. tarda using a biochemical rapid diagnostic identification kit.

키워드

과제정보

This research was supported by Kyungpook National University Research Fund, 2022.

참고문헌

  1. Carlstead K, Shepherdson D. Alleviating stress in zoo animals with environmental enrichment. In: Moberg GP, Mench JA, editors. The biology of animal stress: basic principles and implications for animal welfare. Oxon: CABI publishing. 2000: 337-354. 
  2. Clarridge JE, Musher DM, Fainstein V, Wallace RJ Jr. Extraintestinal human infection caused by Edwardsiella tarda. J Clin Microbiol 1980; 11: 511-514.  https://doi.org/10.1128/jcm.11.5.511-514.1980
  3. Clinical and Laboratory Standards Institute (CLSI). Performance standards for antimicrobial susceptibility testing. Available at: www.nih.org.pk/wp-content/uploads/2021/02/CLSI-2020.pdf. Accessed Aug 1, 2022. 
  4. Coles BM, Stroud RK, Sheggeby S. Isolation of Edwardsiella tarda from three Oregon sea mammals. J Wildl Dis 1978; 14: 339-341.  https://doi.org/10.7589/0090-3558-14.3.339
  5. Collins DM. Ursidae. In: Miller RE, Fowler ME, editors. Fowler's zoo and wild animal medicine. St. Louis: Elsevier Saunders. 2015: 498-508. 
  6. Cools P, Haelters J, Lopes dos Santos Santiago G, Claeys G, Boelens J, Leroux-Roels I, et al. Edwardsiella tarda sepsis in a live-stranded sperm whale (Physeter macrocephalus). Vet Microbiol 2013; 166: 311-315.  https://doi.org/10.1016/j.vetmic.2013.05.020
  7. Fernandez A, Villanueva MP, Gonzalez M, Fernandez F, Latif F, Flores SN, et al. Adhesive and invasive capacities of Edwardsiella tarda isolated from South American sea lion. Braz J Microbiol 2014; 45: 1095-1099.  https://doi.org/10.1590/S1517-83822014000300044
  8. Jung BY, Kim KT, Jeon KY, Kim BH. Antimicrobial susceptibilities and biochemical characteristics of Edwardsiella tarda isolated from zoo animals. J Prev Vet Med 2004; 28: 169-174. 
  9. Kim KT, Kwak D. A case of Aeromonas hydrophila infection due to captivity-induced stress in a spectacled caiman (Caiman crocodilus). J Anim Plant Sci 2013; 23: 1761-1763. 
  10. Kim KT, Lee SH, Kwak D. Prevalence, biochemical characteristics, and antibiotic susceptibility of Aeromonads, Vibrios, and Plesiomonads isolated from different sources at a zoo. J Zoo Wildl Med 2015; 46: 298-305.  https://doi.org/10.1638/2014-0194R.1
  11. Kobolkuti LB, Czirjak GA, Tenk M, Szakacs A, Kelemen A, Spinu M. Edwardsiella tarda associated subcutaneous abscesses in a captive grass snake (Natrix natrix, Squamata: Colubridae). Kafkas Univ Vet Fak Derg 2013; 19: 1061-1063. 
  12. Leotta GA, Pineyro P, Serena S, Vigo GB. Prevalence of Edwardsiella tarda in Antarctic wildlife. Polar Biol 2009; 32: 809-812.  https://doi.org/10.1007/s00300-009-0610-9
  13. Leung KY, Siame BA, Tenkink BJ, Noort RJ, Mok YK. Edwardsiella tarda - virulence mechanisms of an emerging gastroenteritis pathogen. Microbes Infect 2012; 14: 26-34.  https://doi.org/10.1016/j.micinf.2011.08.005
  14. Mendoza SP, Capitanio JP, Mason WA. Chronic social stress: studies in non-human primates. In: Moberg GP, Mench JA, editors. The biology of animal stress: basic principles and implications for animal welfare. Oxon: CABI publishing. 2000: 227-247. 
  15. Nagel P, Serritella A, Layden TJ. Edwardsiella tarda gastroenteritis associated with a pet turtle. Gastroenterology 1982; 82: 1436-1437.  https://doi.org/10.1016/0016-5085(82)90079-8
  16. Nettles RE, Sexton DJ. Successful treatment of Edwardsiella tarda prosthetic valve endocarditis in a patient with AIDS. Clin Infect Dis 1997; 25: 918-919.  https://doi.org/10.1086/515531
  17. Nimmervoll H, Wenker C, Robert N, Albini S. Septicaemia caused by Edwardsiella tarda and Plesiomonas shigelloides in captive penguin chicks. Schweiz Arch Tierheilkd 2011; 153: 117-121.  https://doi.org/10.1024/0036-7281/a000165
  18. Park SB, Aoki T, Jung TS. Pathogenesis of and strategies for preventing Edwardsiella tarda infection in fish. Vet Res 2012; 43: 67. 
  19. Pirarat N, Maita M, Endo M, Katagiri T. Lymphoid apoptosis in Edwardsiella tarda septicemia in tilapia, Oreochromis niloticus. Fish Shellfish Immunol 2007; 22: 608-616.  https://doi.org/10.1016/j.fsi.2006.08.007
  20. Slaven EM, Lopez FA, Hart SM, Sanders CV. Myonecrosis caused by Edwardsiella tarda: a case report and case series of extraintestinal E. tarda infections. Clin Infect Dis 2001; 32: 1430-1433.  https://doi.org/10.1086/320152
  21. Suzuki K, Yanai M, Hayashi Y, Otsuka H, Kato K, Soma M. Edwardsiella tarda bacteremia with psoas and epidural abscess as a food-borne infection: a case report and literature review. Intern Med 2018; 57: 893-897.  https://doi.org/10.2169/internalmedicine.9314-17
  22. Wyatt LE, Nickelson R 2nd, Vanderzant C. Edwardsiella tarda in freshwater catfish and their environment. Appl Environ Microbiol 1979; 38: 710-714. https://doi.org/10.1128/aem.38.4.710-714.1979