Journal of the Korean Society of Visualization (한국가시화정보학회지)

The Korean Society of Visualization (한국가시화정보학회)
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Analysis of Blood Flow after Coil Embolization in Anterior Cerebral Artery Aneurysm

전산해석을 통한 전대뇌동맥류 코일 색전술 후 혈류 유동 분석

  • Donghwi Kim (School of Mechanical Engineering, Pusan National University) ;
  • Jeonghoon Yoon (School of Mechanical Engineering, Pusan National University) ;
  • Changyong Lee (School of Mechanical Engineering, Pusan National University) ;
  • Junwoo Jae (School of Mechanical Engineering, Pusan National University) ;
  • Dongmin Kim (School of Mechanical Engineering, Pusan National University) ;
  • Youngoh Bae (School of Mechanical Engineering, Pusan National University) ;
  • Jinyul Hwang (School of Mechanical Engineering, Pusan National University)
  • Received : 2023.02.24
  • Accepted : 2023.03.22
  • Published : 2023.03.31
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Abstract

We performed numerical simulations of blood flow in an arterial cerebral artery aneurysm to investigate the hemodynamic behavior after coil embolization. A patient-specific model was created based on CTA data. We also conducted the coil embolization simulation to obtain the coil placement within the aneurysm. Blood was assumed to be an incompressible Newtonian fluid, and both the vessel and coil were considered rigid walls. The pulsatile boundary condition was applied at the inlet, and the outflow boundary conditions were used at the outlets. Our findings demonstrated that the coil embolization significantly reduces the blood volume flowrate entering the aneurysm by effectively blocking the inflow jet, leading to a decrease in both TAWSS and WSS, especially at the systolic peak in the impingement zone. While several high OSI regions disappeared over the aneurysm surface, we observed high OSI regions with a relatively small area where the coil did not completely occlude the aneurysm. Overall, these results quantitatively analyzed the effectiveness of coil embolization by focusing on hemodynamic indicators, potentially preventing aneurysm rupture. The present work could contribute to the development of patient-specific coil embolization.

Keywords

Acknowledgement

This work was supported by a National Research Foundation of Korea (NRF) grant funded by the Korea government (MSIT) (Grant No. 2020R1F1A1048537) and supported by Korea Institute of Energy Technology Evaluation and Planning (KETEP) grant funded by the Korea government (MOTIE) (20214000000140)

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