Advances in nano research

  • 제14권3호
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  • Pages.247-259
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  • 2023
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  • 2287-237X(pISSN)
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  • 2287-2388(eISSN)
테크노프레스 (Techno-Press)
권호 표지
DOI QR코드

DOI QR Code

Body action impacts the stability of nanomedicine tools in the drug delivery

  • Peng Zou (Department of Neurosurgery, Yuhuangding Hospital of Yantai) ;
  • Wei Zhao (Department of Neurosurgery, Yuhuangding Hospital of Yantai) ;
  • Jinpeng Dong (Department of Neurosurgery, Yuhuangding Hospital of Yantai) ;
  • Yinyin Cao (Department of Pediatrics, The Affiliated Yantai Yuhuangding Hospital of Qingdao University)
  • Received : 2022.03.24
  • Accepted : 2022.08.18
  • Published : 2023.03.25
⟨ 이전 논문 다음 논문 ⟩

Abstract

Muscle strength and hypertrophy are equivalent when low-intensity resistance exercise is paired with blood flow restriction. This paper deals with the impact of physical exercise in the form of body activities on drug delivery using nanodevices. The body's actions impact the blood flow since the nano drug delivery devices are released into the bloodstream, and physical exercise and all the activities that change the blood flow influence the stability of these nanodevices. The nanodevice for the drug delivery purpose is modeled via nonuniform tube structures based on the high-order beam theory along with the nonlocal strain gradient theory. The nanodevice is made by a central nanomotor as well as two nanoblade in the form of truncated conical nanotubes carrying the nanomedicine. The mathematical simulation of rotating nanodevices is numerically solved, and the effect of various parameters on the stability of nanodevices has been studied in detail after the validation study.

Keywords

Acknowledgement

This work was supported by Shandong Medical and Healthy Science Technology Development Plan (202004040974).

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