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A Case Report of an Elderly Patient with Psoriasis Treated with Jeongri-tang Gagam-bang: Focus on Digestive System Treatment

  • Do Kyung Han (Department of Pharmacology, College of Korean Medicine, Pusan National University) ;
  • Won Gun An (Department of Pharmacology, College of Korean Medicine, Pusan National University)
  • Received : 2023.10.20
  • Accepted : 2023.11.15
  • Published : 2023.12.01

Abstract

Objectives: This study aimed to report the efficacy of Korean medicine with Jeongri-tang Gagam-bang for treating psoriasis. Methods: A patient with psoriasis was treated with Jeongri-tang Gagam-bang (正理湯加減方). Moreover, acupuncture was performed on CV12 (中脘) and both sides of ST25 (天樞), GV20 (百會), LI4 (合谷), and LR3 (太衝) for 15 minutes. Psoriasis severity was assessed using the Psoriasis Area and Severity Index (PASI). Pruritis and dyspepsia intensities were ranked on a Visual Analog Scale (VAS) of 0–10. Results: After treatment, the PASI changed from 21.6 to 1.6. Patient's pruritus had almost disappeared and dyspepsia had improved. Conclusions: This study shows that Jeongri-tang Gagam-bang (正理湯加減方) and acupuncture on CV12 (中脘), ST25 (天樞), GV20 (百會), LI4 (合谷), and LR3 (太衝) might be helpful to treat psoriasis symptoms by improving digestive function.

Keywords

Acknowledgement

This research was supported by Basic Science Research Program through the National Research Foundation of Korea (NRF), funded by the Ministry of Education under grant [No. NRF-2021R1I1A3A04037158].

References

  1. Lee S, Jung S, Lee S. (2021). Comparison of Research Characteristics in Western, Chinese Traditional Medicine and Korean Medicine on Psoriasis. Journal of Korean Medicine, 42(2), 72-81. 
  2. Jeong JY & Han KW. (2009). Common Skin Diseases in Korea. Seoul/Korea: MD world Medical book Co. 168-86. 
  3. Guo X, Zhou D, Sun L, Wang P, Qu J, Zhang C, et al. (2020). Traditional Chinese medicine for psoriasis vulgaris: A Protocol of a prospective, multicenter cohort study. Medicine, 99(41), 1-7 
  4. Hong SH. (2013). Reviewing Research on Korean medical treatment of Psoriasis. J Korean Med Ophthalmol Otolaryngol Dermatol, 26(4), 26-42. 
  5. Lee HC, Choi JH, Kim JH, Jeong MY, Park SY. (2018). A Case Report of Psoriasis treated with Traditional Korean Medicine Including SaengRyoSaMultang-Gamibang and Hwangryunhaedok-tang Herbal-Acupuncture. J Korean Med Ophthalmol Otolaryngol Dermatol, 31(1), 106-16. 
  6. Rui W, Xiangyu D, Fang X, Long G, Yi Y, Wenjuan W, et al. (2017). Metabolic syndrome affects narrow-band UVB phototherapy response in patients with psoriasis. Medicine, 96(50):1-5. 
  7. Han CY, Kim J, Gwang, Seo Y, Kim KS, Kim YB. (2021). Investigation of Effective Korean Herbal Medicine for Psoriasis-Focusing on Lipid Metabolism. J Korean Med Ophthalmol Otolaryngol Dermatol, 34(3), 70-9. 
  8. Kim KH & An KS. (1991). Reflections on Jeongri-tang. Journal of Oriental Physiology and Pathology, 6(1), 207-12. 
  9. Chung WY, Ryu BH, Park DW, Rhu KW. (1998). The efficiency of Jungritang on gastrointestinal organs of rats. Journal of KyungHee Oriental Medicine College, 21(1), 213-23. 
  10. BH Kim, KI Kim, SH Kang, JG Park, DW Kang, HJ Nam, et al. (2018). Explanation and Elaboration of the Clinical Trial Guidelines for Psoriasis Using Herbal Medicine. J Korean Med Ophthalmol Otolaryngol Dermatol, 31(2), 40-59. 
  11. Jeon SW, Jeung CW, Jo HG. (2018). Literature Review on Herbal Medicine Treatment of Psoriasis Based on Chronic Low-grade Inflammation Theory. J Korean Med Ophthalmol Otolaryngol Dermatol, 31(4), 22-30. 
  12. Hirayama A, Oowada S, Ito H, Matsui H, Ueda A, Aoyagi K. (2018). Clinical significance of redox effects of Kampo formulae, a traditional Japanese herbal medicine: comprehensive estimation of multiple antioxidative activities. J Clin Biochem Nutr, 62(1), 39-48. 
  13. Takeshita J, Grewal S, Langan SM, Mehta NN, Ogdie A, Van Voorhees AS, et al. (2017). Psoriasis and comorbid diseases: Epidemiology. Journal of the American Academy of Dermatology, 76(1), 377-90. 
  14. Sorokin A V, Domenichiello AF, Dey AK, Yuan ZX, Goyal A, Rose SM, et al. (2018). Bioactive Lipid Mediator Profiles in Human Psoriasis Skin and Blood. J Invest Dermatol, 138(7), 1518-28. 
  15. Ely PH. (2018). Is psoriasis a bowel disease? Successful treatment with bile acids and bioflavonoids suggests it is. Clin Dermatol, 36(3), 376-89.
  16. Oh JE, Park EJ, Lee HJ. (2007). Effects of HyangsosanGamibang on the PPARγ in the bronchial asthma mouse model. J Korean Oriental Pediatrics, 21(1), 44-51. 
  17. Seo MG, Park YJ, Kang YM, Kim HY, Han I, An HJ. (2022). Comparative Study on Anti-obesity Effects of Pyungwi-san, Magnolia officinalis, and Atractylodes chinensis in High-fat Diet-induced Obese Mouse Model. Nubebe Mibyeong Research Institute, 3(1), 1-12. 
  18. Kim GR, Park WH, Kim JK, Choi DY. (1997). A study on the effects of Changbakleezintang on hyperlipidemia induced by high lipid solid and cholesterol coloid solution in Rats. Korean Journal of Oriental Physiology & Pathology, 11(2), 72-80. 
  19. Shin JW, Son JY, Yim YK, Choi SM, Koo ST, Son CG. (2006). Acupuncture on Siguan Points(LI4 and LR3) Restores Loperamide Scopolamine-induced Intestinal Immotility in Mice. Journal of Korean Oriental Medicine, 27(1), 146-54. 
  20. Kim KS, Kim MH, Sul JU, Kim EJ, Son HS, Na CS. (2023). The Effect of CV12, ST25, ST36 Acupuncture in General Diet and High Fat Diet Rat. Korean Journal of Acupuncture, 40(3), 109-27.