Korean Journal of Clinical Laboratory Science (대한임상검사과학회지)

Korean Society for Clinical Laboratory Science (대한임상검사과학회)
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Spirometry Reference Equations for Asian Migrant Workers in Korea: A Proposal

아시아 외국인 근로자의 폐활량검사 결과해석을 위한 예측식 제안

  • Hwa-Yeon LEE (Occupational Health Research Bureau, Occupational Safety and Health Research Institute) ;
  • Yonglim WON (Occupational Health Research Bureau, Occupational Safety and Health Research Institute)
  • 이화연 (산업안전보건연구원 직업건강연구실) ;
  • 원용림 (산업안전보건연구원 직업건강연구실)
  • Received : 2023.02.15
  • Accepted : 2023.03.09
  • Published : 2023.03.31
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Abstract

This study proposes a spirometry reference equation suitable for Asian migrant workers undergoing special health examinations. The study participants were divided according to their region: Central Asia, Northeast Asia, and South Asia Pacific. We confirmed results of the spirometry analysis of migrant workers and the interpretation consistency between the prediction equations. Based on this data, we propose a reference equation suitable for domestic migrant workers and suggest a scaling factor applicable to the spirometer wherein the reference equation is not easily applicable. The kappa-values obtained for men and women, respectively, between the global lung function initiative 2012 (GLI2012)-Southeast Asian and the Southeast Asian equations were 0.819 and 0.770, between the GLI2012-Southeast Asian and the South Asian equations were 0.881 and 0.866, and between the GLI2012-Northeast Asian and the Central Asian equations were 0.831 and 0.833. We propose applying the GLI2012-Northeast Asian equation for Northeast Asian and Central Asian countries, whereas the GLI2012-Southeast Asian equation was found to be more suitable for predicting Southeast Asian and South Asian populations. For spirometry, we recommend applying a scaling factor of 0.87 to the Dr. Choi equation, wherein the GLI2012-Southeast Asian equation is not applicable.

이 연구는 특수건강진단 폐활량검사 시 아시안 외국인 근로자들에게 적절한 예측식을 제안하는 것이다. 연구 대상은 지리적 분포에 따라 중앙아시아, 동북아시아, 남아시아태평양 그룹으로 나누었으며, 그룹별 폐활량검사 결과와 예측식간 일치도를 확인하였다. 이를 기준으로 국내 외국인 근로자들에게 폐활량검사 시 적절한 예측식을 제안하였고, 제안한 예측식을 적용할 수 없는 폐활량검사기에는 보정계수를 제안하였다. Global lung function initiative 2012 (GLI2012)-동북아시안식과 동남아시안식의 해석일치도는 남성 0.819, 여성 0.770이었고, GLI2012-동남아시안식과 남아시안식의 해석 일치도는 남성 0.881, 여성 0.886이었다. GLI2012-동북아시안식과 중앙아시안식의 해석일치도는 남성 0.831, 여성 0.833이었다. 따라서 동북아시안, 중앙아시안 그룹에 속하는 외국인 근로자는 GLI2012-동북아시안식을 적용하고, 동남아시안, 남아시안 그룹에 속하는 외국인 근로자는 GLI2012-동남아시안식을 제안한다. GLI2012-동남아시안식을 선택할 수 없는 폐활량검사기의 경우 최정근식(Dr. Choi equation)에 보정계수 0.87을 적용할 것을 제안한다.

Keywords

Acknowledgement

This research was supported by Occupational Safety and Health Research Institute. This article is based on a part of the first author's master's thesis.

References

  1. MinistryofEmployment and Labor.Occupationalsafetyandhealth acts [Internet]. Sejong: Ministry of Employment and Labor [cited 2021 January 15]. Available from: https://www.law.go.kr/LSW/lsInfoP.do?efYd=20220818&lsiSeq=234717#0000 
  2. Townsend MC; Occupational and Environmental Lung Disorders Committee. Spirometry in the occupational health setting--2011 update. J Occup Environ Med. 2011;53:569-584. https://doi.org/10.1097/JOM.0b013e31821aa964 
  3. Lee HY, Won YL, et al. Reference equation of spirometry migrant workers in Korea. 2021-OSHRI-745. Ulsan: Occupational Safety and Health Research Institute; 2021.
  4. Lung function testing: selection of reference values and interpretative strategies. American Thoracic Society. Am Rev Respir Dis. 1991;144:1202-1218. https://doi.org/10.1164/ajrccm/144.5.1202 
  5. WorldData.info.Weightandsize inCambodia [Internet].Oldenburg: WorldData.info [cited 2021 June 5]. Available from: https://www.worlddata.info/asia/cambodia/health.php 
  6. Ministry of Employment and Labor. e-Employment and labor indicators; migrant workers by country(E-9 Visa) number of employees [Internet]. Sejong: Ministry of Employment and Labor [cited 2021 June 5]. Available from: https://eboard.moel.go.kr/indicator/detail?menu_idx=75 
  7. KimN, Kim SY,Song Y,SuhC, Kim KH,Kim JH, etal.Theeffect of applying ethnicity-specific spirometric reference equations to Asian migrant workers in Korea. Ann Occup Environ Med. 2015;27:14. https://doi.org/10.1186/s40557-015-0065-0 
  8. Crapo RO, Jensen RL, Oyunchimeg M, Tsh T, DuWayne Schmidt C. Differences in spirometry reference values: a statistical comparison of a Mongolian and a Caucasian study. Eur Respir J. 1999;13:606-609. https://doi.org/10.1183/09031936.99.13360699 
  9. Gnanou J, Caszo B, Mohamad WH, Nawawi H, Yusoff K, Ismail T. Prediction equations for lung function in healthy, life time never-smoking Malaysian population. Southeast Asian J Trop Med Public Health. 2011;42:965-976. 
  10. Memon MA, Sandila MP, Ahmed ST. Spirometric reference values in healthy, non-smoking, urban Pakistani population. J Pak Med Assoc. 2007;57:193-195. 
  11. Choi JK, Paek D, Lee JO. Normal predictive values of spirometry in Korean population. Tuberc Respir Dis. 2005;58:230-242. https://doi.org/10.4046/trd.2005.58.3.230 
  12. Quanjer PH, Stanojevic S, Cole TJ, Baur X, Hall GL, Culver BH, et al. Multi-ethnic reference values for spirometry for the 3-95-yr age range: the global lung function 2012 equations. Eur Respir J. 2012;40:1324-1343. https://doi.org/10.1183/09031936.00080312 
  13. McHugh ML. Interrater reliability: the kappa statistic. Biochem Med (Zagreb). 2012;22:276-282.  https://doi.org/10.11613/BM.2012.031
  14. Occupational Safety and Health Research Institute. Guidelines for Workers' Health Examination. 2021-OSHIRI-805. Ulsan: Occupational Safety and Health Research Institute; 2021. p169-170. 
  15. Eom SY, Kim H. Reference values for the pulmonary function of Korean adults using the data of Korea National Health and Nutrition Examination Survey IV (2007-2009). J Korean Med Sci. 2013;28:424-430. https://doi.org/10.3346/jkms.2013.28.3.424 
  16. JoBS,MyongJP,RheeCK,Yoon HK,Koo JW,KimHR.Reference values for spirometry derived using Lambda, Mu, Sigma (LMS) method inKorean adults: in comparison withprevious references. J Korean Med Sci. 2018;33:e16. https://doi.org/10.3346/jkms.2018.33.e16 
  17. Won YL, Kim EA, et al. Development of pulmonary function test guidelines for special and pneumoconiosis health examination. 2020-OSHIRI-820. Ulsan: Occupational Safety and Health Research Institute; 2020. p15-26. 
  18. Won YL, Kim EA, etal.Currentstatus ofandmeasurestostandardize spirometry findings in special health examinations. 2019-OSHRI-1533. Ulsan: Occupational Safety and Health Research Institute; 2019. p11. 
  19. Won Y, Lee HY. A proposal of spirometry reference equations for Korean workers. Ann Occup Environ Med. 2022;34:e14. https://doi.org/10.35371/aoem.2022.34.e14