Acknowledgement
This study was supported by the National Research Foundation of Korea (NRF2021R1 A6A1A03040260, NRF2021R1A2C2005472), Korean Health Technology R&D Project, Ministry of Health & Welfare, Republic of Korea (KHIDIHI21C00710), and by a grant from Asan Institutes for Life Sciences (AILS), grant No. 2020IP0060-1.