Journal of Animal Reproduction and Biotechnology (한국동물생명공학회지)

The Korean Society of Animal Reproduction and Biotechnology (한국동물생명공학회)
권호 표지
DOI QR코드

DOI QR Code

Morphological differences according to uterine tissue remodeling during estrus between sika deer and water deer

  • Min-Gee Oh (General Graduate School of Animal life Convergence Science, Hankyong National University) ;
  • Yong-Su Park (Research Center for Endangered Species, National Institute of Ecology) ;
  • Sang-Hwan Kim (General Graduate School of Animal life Convergence Science, Hankyong National University)
  • Received : 2023.12.04
  • Accepted : 2023.12.09
  • Published : 2023.12.31
Download PDF
⟨ Previous Next ⟩

Abstract

Background: Water deer and sika deer, which breed in the wild environment, are known to have similar reproductive physiology mechanisms. Therefore, this study aimed to analyze the differences in uterine development between water deer and sika deer during estrus. Methods: MMPs and uterine development-related factors were analyzed and morphological differences were compared in the uterus of sika deer captured near Russia near Korea and water deer captured in the wild in Korea. Results: In terms of morphological differences in the uterus, the glands that form villus within the endometrium of the water deer were newly developed, and the formation of small glands was high, but the villus and glands of the sika deer were expanded, and the stroma zone in the myometrium was higher than that of the water deer. Development has increased. Additionally, the expression of PAPP-A and VEGF factors was increased in the endometrium of water deer than in sika deer, but the actions of MMPs were increased in sika deer. Conclusions: As a result of this study, there is a significant difference in the development of glands in the endometrium of water deer and sika deer during estrus, and it is believed that there is a significant difference in the development of the uterus due to the physiological effects of estrus between water deer and sika deer. Additionally, it is believed that there will be differences in the timing at which pregnancy can be decided.

Keywords

Acknowledgement

The authors sincerely thank the Research Center for Endangered Species and the National Institute of Ecology for their support in conducting this study.

References

  1. Asher GW, Monfort SL, Wemmer C. 1999a. Comparative reproductive function in cervids: implications for management of farm and zoo populations. J. Reprod. Fertil. Suppl. 54:143-156.
  2. Asher GW, Scott IC, Mockett BG, O'Neill KT, Diverio S, Inskee EK, Townsend EC. 1999b. Ultrasonographic monitoring of ovarian function during the oestrous cycle of fallow deer (Dama dama). In: Zoltan Z (Ed.), Advances in Deer Biology: Proceedings of the 4th International Deer Biology Congress: 30 June-4 July, 1998 Kaposvar, Hungary, Pannon University of Agriculture Faculty of Animal Science, Kaposvar, pp. 148-152.
  3. Chen XM, Wei HJ, Yang YF, Xue HL, Zhao WG, Zhao M. 2015. Serum hormone concentrations and ovarian follicular wave emergence in Jilin sika deer (Cervus nippon hortulorum) after synchronization of estrous cycles. Anim. Reprod. Sci. 153:44-49. https://doi.org/10.1016/j.anireprosci.2014.11.017
  4. Hamasaki S, Yamauchi K, Ohki T, Murakami M, Takahara Y, Takeuchi Y, Mori Y. 2001. Comparison of various reproductive status in sika deer (Cervus nippon) using fecal steroid analysis. J. Vet. Med. Sci. 63:195-198. https://doi.org/10.1292/jvms.63.195
  5. Kim SH, Kim KL, Lee JH, Shin DH, Jung NH, Lee HJ, Yoon JT. 2018. Detection of matrix metalloproteinases patterns in bovine luteum cell during pregnancy. J. Emb. Trans. 33:61-68. https://doi.org/10.12750/JET.2018.33.2.61
  6. Kim SH, Lee HJ, Lee JY, Park YS, Yoon JT. 2014a. Physiological difference of estrus and pregnant ovary in Korean water deer. J. Emb. Trans. 29:43-50. https://doi.org/10.12750/JET.2014.29.1.43
  7. Kim SH, Shin YS, Kang MH, Yoon JT, Min KS. 2014b. Gene expression and localization of 20α-hydroxysteroid dehydrogenase (HSD) in reproductive tissues during early pregnancy of cattle. Anim. Reprod. Sci. 147:1-9. https://doi.org/10.1016/j.anireprosci.2014.03.016
  8. Kotlarczyk AM, Grzyb M, Korzekwa AJ. 2021. Regulation of uterine function during estrous cycle, anestrus phase and pregnancy by steroids in red deer (Cervus elaphus L.). Sci. Rep. 11:20109.
  9. Kumar A, Banerjee A, Singh D, Thakur G, Kasarpalkar N, Gavali S, Gadkar S, Madan T, Mahale SD, Balasinor NH, Sachdeva G. 2018. Estradiol: a steroid with multiple facets. Horm. Metab. Res. 50:359-374. https://doi.org/10.1055/s-0044-100920
  10. Lee JH, Park YS, Oh MG, Kim SH. 2023. Apoptosis and remodeling in ovary of water deer and sika deer at pregnant and non-pregnant stages. Open Agric. J. 17:e187433152301240.
  11. McCorkell R, Woodbury M, Adams GP. 2006. Ovarian follicular and luteal dynamics in wapiti during the estrous cycle. Theriogenology 65:540-556. https://doi.org/10.1016/j.theriogenology.2005.05.049
  12. Oh MG and Kim SH. 2022. Morphological remodeling in mouse vagina due to hormonal hypersecretion. J. Anim. Reprod. Biotechnol. 37:42-47. https://doi.org/10.12750/JARB.37.1.42
  13. Sohn JH and Kimura J. 2012. Observation of male reproductive organ in Korean water deer (Hydropotes inermis argyropus). Asian J. Anim. Vet. Adv. 7:30-37. https://doi.org/10.3923/ajava.2012.30.37
  14. Sohn JH, Yamane S, Saitoh Y, Kusakabe KT, Kimura J, Kiso Y. 2021. Morphology of placentome in Korean water deer Hydropotes inermis argropus. J. Vet. Med. Sci. 83:1081-1085. https://doi.org/10.1292/jvms.21-0158
  15. Spencer TE, Hayashi K, Hu J, Carpenter KD. 2005. Comparative developmental biology of the mammalian uterus. Curr. Top. Dev. Biol. 68:85-122. https://doi.org/10.1016/S0070-2153(05)68004-0
  16. Tsafriri A. 1995. Ovulation as a tissue remodelling process. Proteolysis and cumulus expansion. Adv. Exp. Med. Biol. 377:121-140. https://doi.org/10.1007/978-1-4899-0952-7_8
  17. Wooding FBP, Osborn D, Killian GJ. 2018. Trinucleate uterine epithelial cells as evidence for White-tail Deer trophoblast binucleate cell migration and as markers of placental binucleate cell dynamics in a variety of wild ruminants. Placenta 62:34-42. https://doi.org/10.1016/j.placenta.2017.12.012
  18. Yanagawa Y, Matsuura Y, Suzuki M, Katagiri S, Tsubota T. 2008. Immunohistochemical localization of the estrogen receptor alpha (ERalpha) and progesterone receptor (PR) in the uterus of sika deer (Cervus nippon) during pregnancy. Jpn. J. Vet. Res. 56:139-149.