과제정보
본 연구는 산업통상자원부와 한국산업기술진흥원의 "사회적경제혁신성장사업" (과제번호 P0017625)과, 2022년도 정부재원 (과학기술정보통신부 여성과학기술인 R&D 경력복귀 지원사업)으로 한국여성과학기술인육성재단의 지원 (협약번호 제 2022-339호)을 받아 연구되었습니다.
참고문헌
- Statistics Korea. Causes of Death Statistics 2021 [cited 2022 Dec 13]. Available form : URL : https://kosis.kr/statHtml/statHtml.do?orgId=101&tblId=DT_1B34E01&conn_path=I2
- Chae HB. Review: Alcoholic Liver Disease. Kor. J. Gastroenterol. 2009 ; 53(5) : 275-82. https://doi.org/10.4166/kjg.2009.53.5.275
- Kwon MH, Min KJ, Kim YC. Inhibitory Effects of Peonia japonica Water Extract on Skin Aging (I) - Focussed on Alleviative Effects of Inflammation and Skin Barrier Damage -. J. Environ. Toxicol. 2009 ; 24(2) : 159-67.
- Mun YJ. Anti-inflammatory activity of jakyakgamcho-tang on Lipopolysaccharide-Stimulated BV-2 Microglia Cells. Kor. J. Herbology. 2022 ; 37(5) : 83-8.
- Kim MR, Kang OH, Kim SB, Kang HJ, Kim JE, Hwang HC. The Study of Anti-inflammatory Effect of Hwanggeumjakyak-tang Extract in RAW 264.7 Macrophage. Kor. J. Herbology. 2013 ; 28(1) : 43-50. https://doi.org/10.6116/KJH.2013.28.1.43
- Chan K, Liu ZQ, Jiang ZH, Zhou H, Wong YF, Xu H-X, Liu L. The effects of sinomenine on intestinal absorption of paeoniflorin by the everted rat gut sac model. J. Ethnopharmacol. 2006 ; 103(3) : 425-32. https://doi.org/10.1016/j.jep.2005.08.020
- Yang HO, Ko WK, Kim JY, Ro HS. Paeoniflorin: an antihyperlipidemic agent from Paeonia lactiflora. Fitoterapia. 2004 ; 75(1) : 45-9. https://doi.org/10.1016/j.fitote.2003.08.016
- Sugaya A, Suzuki T, Sugaya E, Yuyama N, Yasuda K, Tsuda T. Inhibitory effect of peony root extract on pentylenetetrazol-induced EEG power spectrum changes and extracellular calcium concentration changes in rat cerebral cortex. J. Ethnopharmacol. 1991 ; 33(1-2) : 159-67. https://doi.org/10.1016/0378-8741(91)90174-C
- Fan LL, O'Keefe DD, Powell WW Jr. Pharmacologic studies on radix puerariae: effect of puerarin on regional myocardial blood flow and cardiac hemodynamics in dogs with acute myocardial ischemia. Chin. Med. J. 1985 ; 98(11) : 821-32.
- Chiao CY, Kwon HJ, Jeong JS, Lee JH, Hong SP. Determination Method of Puerarin and Daidzin from Puerariae Radix by Reversed-Phase HPLC with Pulsed Amperometric Detection. Kor. J. Herbology. 2008 ; 23(4) : 171-7.
- Keung WM, Vallee BL. Daidzin: a potent, selective inhibitor of human mitochondrial aldehyde dehydrogenase. PNAS. 1993 ; 90(4) : 1247-51. https://doi.org/10.1073/pnas.90.4.1247
- Keung WM, Vallee BL. Therapeutic lessons from traditional Oriental medicine to contemporary Occidental pharmacology. EXS. 1994 ; 71 : 371-81.
- Singleton V, Rossi J. Colorimetry of Total Phenolic Compounds with Phosphomolybdic-Phosphotungstic Acid Reagents. Am. J. Enol. Vitic. 1965 ; 16 : 144-58. https://doi.org/10.5344/ajev.1965.16.3.144
- Woisky R, Salatino, A. Analysis of Propolis: Some Parameters and Procedures for Chemical Quality Control. J. Apic. Res. 1998 ; 37 : 99-105. https://doi.org/10.1080/00218839.1998.11100961
- Blois M. Antioxidant Determinations by the Use of a Stable Free Radical. Nature. 1958 ; 181 : 1199-200. https://doi.org/10.1038/1811199a0
- Re R, Pellegrini N, Proteggente A, Pannala A, Yang M, Rice-Evans C. Antioxidant activity applying an improved ABTS radical cation decolorization assay. Free Radic. Biol. Med. 1999 ; 26(9-10) : 1231-7. https://doi.org/10.1016/S0891-5849(98)00315-3
- Ali S, LeBel C, Bondy S. Reactive Oxygen Species Formation as a Biomarker of Methylmercury and Trimethyltin Neurotoxicity. Neurotoxicology. 1992 ; 13 : 637-48.
- Kooy NW, Royall JA, Ischiropoulos H, Beckman JS. Peroxynitrite-mediated oxidation of dihydrorhodamine 123. Free Radic. Biol. Med. 1994 ; 16(2) : 149-56. https://doi.org/10.1016/0891-5849(94)90138-4
- Mihara M, Uchiyama M. Determination of malonaldehyde precursor in tissues by thiobarbituric acid test. Anal. Biochem. 1978 ; 86(1) : 271-8. https://doi.org/10.1016/0003-2697(78)90342-1
- Hur K, Park IK. Clinical Usefulness of Direct/Total Bilirubin Ratio. Lab. Med. Online. 2018 ; 8(4) : 127-34. https://doi.org/10.3343/lmo.2018.8.4.127
- Devasagayam TP, Tilak JC, Boloor KK, Sane KS, Ghaskadbi SS, Lele RD. Free radicals and antioxidants in human health: current status and future prospects. J. Assoc. Physicians India. 2004 ; 52 : 794-804.
- Lan T, Kisseleva T, Brenner DA. Deficiency of NOX1 or NOX4 Prevents Liver Inflammation and Fibrosis in Mice through Inhibition of Hepatic Stellate Cell Activation. PLoS One. 2015 ; 10(7) : e0129743.
- Sies H, Jones D.P. Reactive oxygen species (ROS) as pleiotropic physiological signalling agents. Nat. Rev. Mol. Cell. Biol. 2020 ; 21 : 363-83. https://doi.org/10.1038/s41580-020-0230-3
- Esterbauer H, Schaur RJ, Zollner H. Chemistry and biochemistry of 4-hydroxynonenal, malonaldehyde and related aldehydes. Free. Radic. Biol. Med. 1991 ; 11(1) : 81-128. https://doi.org/10.1016/0891-5849(91)90192-6
- Baraona E, Lieber CS. Effects of ethanol on lipid metabolism. J. Lipid Res. 1979 ; 20(3) : 289-315. https://doi.org/10.1016/S0022-2275(20)40613-3
- Hashimoto T, Cook WS, Qi C, Yeldandi AV, Reddy JK, Rao MS. Defect in peroxisome proliferator- activated receptor alpha-inducible fatty acid oxidation determines the severity of hepatic steatosis in response to fasting. J. Biol. Chem. 2000 ; 275(37) : 28918-28. https://doi.org/10.1074/jbc.M910350199
- Lee SH, Jung JY, Park SM, Jegal KH, Byun SH, Cho IJ, Kim SC, Kim KJ, Kim YW. Hepatoprotective Effect of Paeoniae Radix via Nrf2 Activation. Kor. J. Herbology. 2016 ; 31(1) : 33-40. https://doi.org/10.6116/KJH.2016.31.1.33.
- Hyun DH, Jung SY, Jung SS, Ha KT, Kim CH, Kim DW, Kim JK, Choi DY. The Study of Protective Effect of Puerariae Radix against CCl4-induced Hepatotoxicity. J Physiol & Pathol Korean Med 2003 ; 17(2) : 297-307.
- Lee SH, Shin MR, Lee JH, Roh SS. Effects of water extract of Paeoniae Radix Alba on a thioacetamide induced acute liver injury rat model. J. Nutr. Health. 2021 ; 54(2) : 224-37. https://doi.org/10.4163/jnh.2021.54.2.224
- Kim OK. Protective Effects of Extract of Puerariae Radix on Hepatic Injury Induced by Carbon Tetrachloride In Rat. KOCS. 2017 ; 34(3) : 443-50.
- Kim JO, Kim SJ, Kim JB, Nam WH, Lee JB, Lee HD. Comparison of Ingredient and Efficacy of Galgeuntang (Gegen-tang) Mix Extract Powder and Decoction. JPPKM. 2019 ; 33(1) : 39-47. https://doi.org/10.15188/kjopp.2019.02.33.1.39
- Perron NR, Brumaghim JL. A review of the antioxidant mechanisms of polyphenol compounds related to iron binding. Cell. Biochem. Biophys. 2009 ; 53(2) : 75-100. https://doi.org/10.1007/s12013-009-9043-x
- Sies H, Jones DP. Reactive oxygen species (ROS) as pleiotropic physiological signalling agents. Nat. Rev. Mol. Cell Biol. 2020 ; 21(7) : 363-83. https://doi.org/10.1038/s41580-020-0230-3
- Hordijk PL. Regulation of NADPH oxidases: the role of Rac proteins. Circ. Res. 2006 ; 98(4) : 453-62. https://doi.org/10.1161/01.RES.0000204727.46710.5e
- Sea K, Sohn SH, Durazo A, Sheng Y, Shaw BF, Cao X, Taylor AB, Whitson LJ, Holloway SP, Hart PJ, Cabelli DE, Gralla EB, Valentine JS. Insights into the role of the unusual disulfide bond in copperzinc superoxide dismutase. J. Biol. Chem. 2015 ; 290(4) : 2405-18. https://doi.org/10.1074/jbc.M114.588798
- You M, Fischer M, Deeg MA, Crabb DW. Ethanol induces fatty acid synthesis pathways by activation of sterol regulatory element-binding protein (SREBP). J. Biol. Chem. 2002 ; 277(32) : 29342-7. https://doi.org/10.1074/jbc.M202411200
- Shim JJ. Secondary Causes of Fatty Liver. STS. 2018 ; 2018(2) : 16-22.
- Lee W, Seo YK. SREBP as a Global Regulator for Lipid Metabolism. J. Life. Sci. 2018 ; 28(10) : 1233-43. https://doi.org/10.5352/JLS.2018.28.10.1233
- Lemberger T, Desvergne B, Wahli W. Peroxisome proliferator-activated receptors: a nuclear receptor signaling pathway in lipid physiology. Annu. Rev. Cell Dev. Biol. 1996 ; 12 : 335-63. https://doi.org/10.1146/annurev.cellbio.12.1.335