대한한방내과학회지 (The Journal of Internal Korean Medicine)

대한한방내과학회 (The Society of Internal Korean Medicine)
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Herbal Medicine for the Treatment of Non-Erosive Reflux Disease: A Systematic Review and Meta-Analysis Protocol

  • Minjeong Kim (Dept. of Clinical Korean Medicine, Graduate School of Kyung Hee University) ;
  • Chaehyun Park (Dept. of Clinical Korean Medicine, Graduate School of Kyung Hee University) ;
  • Jae-Woo Park (Dept. of Digestive Diseases, College of Korean Medicine, Kyung Hee University) ;
  • Jinsung Kim (Dept. of Digestive Diseases, College of Korean Medicine, Kyung Hee University) ;
  • Seok-Jae Ko (Dept. of Digestive Diseases, College of Korean Medicine, Kyung Hee University)
  • 투고 : 2023.11.16
  • 심사 : 2023.12.22
  • 발행 : 2023.12.30
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초록

Introduction: Non-erosive reflux disease (NERD) is the most common subtype of gastroesophageal reflux disease (GERD). This study aims to synthesize evidence on the efficacy and safety of various herbal medicines for the treatment of NERD. Methods and analysis: Ten electronic databases will be examined: MEDLINE (via PubMed), Cochrane Central Register of Controlled Trials, Embase, Allied and Complementary Medicine Database, China National Knowledge Infrastructure Database, Citation Information by Nii, Korean Medical Database, Korean Studies Information Service System, National Digital Science Library, and Oriental Medicine Advanced Searching Integrated System. All randomized controlled trials published from inception to May 2023 that meet the eligibility criteria will be selected. Two independent researchers will extract data, such as publication year, study design, intervention details, outcome measures, main results, and adverse events. The risk of bias and quality of evidence will be assessed, and subgroup analyses will be performed according to the type of control intervention and herbal medicine. The analysis process will be conducted using Review Manager 5.4 software. Discussion: This review will present a summary and rationale for herbal medicine's effectiveness in treating NERD. The findings of this review can help those who want to apply herbal medicine to the treatment of NERD.

키워드

과제정보

This work was supported by a National Research Foundation of Korea (NRF) grant funded by the Korean government (MSIT) (No. 2022R1C1C1004937) to S.J.K..

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