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Clinical Assessment of Lip Balm Containing Exfoliation Complex to Improve Wrinkles, Elasticity, and Hydration of Lips

입술의 주름, 탄력, 보습 개선을 위한 각질 박리 복합물이 함유된 립밤의 임상 효능 평가

  • Jiye Park (LG Household & Health Care Ltd., LG Science Park) ;
  • Jae Young Shin (LG Household & Health Care Ltd., LG Science Park) ;
  • Jinyong Lee (LG Household & Health Care Ltd., LG Science Park) ;
  • Myoung Jin An (LG Household & Health Care Ltd., LG Science Park) ;
  • Nae Gyu Kang (LG Household & Health Care Ltd., LG Science Park)
  • 박지예 (LG 생활건강 기술연구원 R&I 연구소) ;
  • 신재영 (LG 생활건강 기술연구원 R&I 연구소) ;
  • 이진용 (LG 생활건강 기술연구원 R&I 연구소) ;
  • 안명진 (LG 생활건강 기술연구원 R&I 연구소) ;
  • 강내규 (LG 생활건강 기술연구원 R&I 연구소)
  • Received : 2023.11.20
  • Accepted : 2023.12.27
  • Published : 2023.12.30

Abstract

Lips have a unique desquamation process and moisturizing properties that are structurally different from ordinary skin. In particular, the turnover cycle of the stratum corneum is fast and the outermost stratum corneum is thin, so the amount of keratin is relatively high, and there are no skin appendages, so it is very vulnerable to maintaining moisture. In this study, we set three targets for lip care : stratum corneum, moisture, and barrier, and aimed to identify the potential of three target-specific ingredients for lips improvement. We confirmed the exfoliating, moisturizing, and barrier improvement efficacy of three target-specific ingredients which also have mild exfoliating effect. Specifically, we verified that Bacillus clausii extract improved skin exfoliation, gluconolactone improved skin moisture retention, and serine reinforced skin barrier function. To test the in vivo efficacy of the complex composed of three target-specific ingredients on the human lips, the lip balm manufactured with non-irritating range of concentration was applied, and we confirmed that it was effective in improving lip exfoliation·moisturizing·elasticity·wrinkles. Consequently, it was confirmed that the beauty and health indicators of the lips could be improved through the exfoliation-moisturization-barrier care of the lips and these ingredients were applied to LG H&H LIPCERIN products.

입술은 구조적으로 일반 피부와 다른 특유의 각질, 보습 특성을 갖는다. 특히, 각질의 턴오버 주기가 빠르고 최외곽 각질층이 얇아 비교적 각질의 발생량이 많고, 부속기관이 존재하지 않아 수분 유지에 매우 취약한 환경을 가지고 있다. 본 연구에서는 새롭게 개발될 립케어 제품의 타겟을 각질-보습-장벽 세 가지로 설정하고 각 맞춤 소재의 개선 가능성을 확인하는 것을 목표로 하여 각질 박리 효능이 있는 소재 3 종에 대해, 각질, 보습, 장벽 개선 효능을 검증하였다. 구체적으로 Bacillus clausii extract에 의한 각질 개선, 글루코노락톤에 의한 피부 수분 보유량 개선, 세린에 의한 장벽 기능 강화 효능을 확인하였다. 립케어의 인체 효능 검증을 위해 각 효능 성분의 자극이 없는 범위의 농도를 설정하여 립밤 제조 및 인체 효능 평가를 진행하였고, 입술 각질·보습·탄력·주름 개선의 효능이 있음을 확인할 수 있었다. 결과적으로 입술의 각질-보습-장벽 케어를 통해 입술의 미용, 건강 지표가 개선될 수 있음을 확인하고 해당 소재들을 립세린 제품에 적용하였다.

Keywords

References

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