Journal of the Society of Cosmetic Scientists of Korea (대한화장품학회지)

Society of Cosmetic Scientists of Korea (대한화장품학회)
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Development of a Skin Index Using Skin Characteristic Factors and Skin Biomarkers of Korean Women According to H igh Temperature and Low Humidity Environments

고온건조 환경에 따른 한국 여성의 피부 특성인자와 피부 바이오 마커를 활용한 피부 지수 개발

  • 맹지혜 ((주)유로핀즈씨알에이) ;
  • 남개원 (서원대학교 바이오코스메틱학과)
  • Received : 2023.10.31
  • Accepted : 2023.12.07
  • Published : 2023.12.30
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Abstract

In this study, basic skin characteristic data was measured by measuring skin hydration, skin sebum secretion rate, skin melanin index, skin redness index, skin redness image analysis, transepidermal water loss (TEWL), and amount of stratum corneum before and after creating a temporary high temperature and low humidity environments targeting Korean women in their 20s to 50s. Stratum corneum by tape stripping was collected at each measurement and skin biomarkers including total protein content, carbonylated protein, neutral lipid, and lipid peroxidation were analyzed. Based on the results, the differences before and after creating a high temperature and low humidity environments were confirmed, the correlation between skin characteristics and skin biomarkers was confirmed, and a new skin index was created based on this. The new skin index can be used in product efficacy evaluation, and the possibility of constructing a new clinical study method and using skin biomarker discovery research through additional research was confirmed.

본 연구에서는 20 ~ 50 대 한국 여성을 대상으로 일시적 고온건조 환경 조성 전후 피부 수분량, 피부 유분량, 피부 멜라닌, 피부 붉은기, 피부 붉은기 이미지 분석, 경피수분손실량, 피부 각질량을 측정하여 기초 피부 특성 데이터를 수집하였으며, 측정시기 별 각질 채취를 진행하여 피부 바이오마커 중 총단백질량, 카르보닐화 단백질, 중성 지질, 지질 과산화를 분석하였다. 해당 결과를 기반으로 고온건조 환경 조성 전후의 차이를 확인하고, 피부 특성과 피부 바이오마커의 상관성을 확인하였으며, 이를 기반으로 신규 피부 지수를 만들었다. 신규 피부 지수는 제품 효능평가에 반영이 가능하며 추가연구를 통한 신규 인체적용시험법 구성 및 피부 바이오마커 발굴 연구 활용 가능성을 확인하였다.

Keywords

Acknowledgement

본 연구는 2022년도 중소벤처기업부의 재원으로 중소기업기술정보진흥원의 지원을 받아 수행된 창업성장기술개발사업(디딤돌)의 결과로(S3308700) 이에 감사를 드립니다.

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