Childhood Kidney Diseases

Korean Society of Pediatric Nephrology (대한소아신장학회)
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Renal artery stenosis presenting as congenital nephrotic syndrome with hyponatremic hypertensive syndrome in a 2-month-old infant: a case report

  • Dabin Kim (Department of Pediatrics, Seoul National University Children's Hospital) ;
  • Yo Han Ahn (Department of Pediatrics, Seoul National University Children's Hospital) ;
  • Hee Gyung Kang (Department of Pediatrics, Seoul National University Children's Hospital) ;
  • Ji Hyun Kim (Department of Pediatrics, Seoul National University College of Medicine) ;
  • Seon Hee Lim (Department of Pediatrics, Pusan National University Children's Hospital, Pusan National University School of Medicine)
  • Received : 2023.10.08
  • Accepted : 2023.11.16
  • Published : 2023.12.31
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Abstract

Here, we present the case of a 2-month-old male infant with hyponatremic hypertensive syndrome resulting from stenosis of the right proximal and mid-renal arteries. The patient exhibited nephrotic-range proteinuria, low serum albumin, increased serum creatinine, and elevated renin and aldosterone levels. Doppler ultrasonography and computed tomography angiography revealed decreased vascular flow in the small right renal artery. Following a successful percutaneous balloon angioplasty, the patient experienced a decrease in blood pressure and normalization of serum electrolyte levels within a few days. However, it took 3 months for the proteinuria to resolve completely. This case is significant as it represents the first reported instance of a neonate presenting with clinical features resembling congenital nephrotic syndrome caused by renal artery stenosis that was successfully treated with percutaneous renal angioplasty.

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References

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