Korean Journal of Veterinary Service (한국동물위생학회지)

The Korean Society of Veterinary Service (한국동물위생학회)
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A case of splenic extraskeletal mesenchymal chondrosarcoma in a Yorkshire Terrier dog

  • Eunhye Jung (Gyeongbuk Veterinary Service Laboratory) ;
  • Hyoung-Seok Yang (Jeju Self-Governing Provincial Veterinary Research Institute) ;
  • Ji-Youl Jung (College of Veterinary Medicine and Veterinary Medical Research Institute, Jeju National University) ;
  • Jae-Hoon Kim (College of Veterinary Medicine and Veterinary Medical Research Institute, Jeju National University)
  • Received : 2023.11.15
  • Accepted : 2023.12.13
  • Published : 2023.12.30
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Abstract

A 7-year-old male Yorkshire Terrier dog was present to an animal clinic and a large soft mass was found in the spleen by radiological examination, and total splenorectomy was performed. Grossly, a large protruded splenic mass was soft to moderately firm and multilobulated. On the cut surface, the mass was off-white to tan, dark red, and rust colored with many cavitation and had gelatinous areas. Histologically, the tumor cells were characterized by coexistence of the primitive mesenchymal tissues and mature or immature cartilage tissues. Primitive mesenchymal areas were composed of round/oval or spindle shaped immature cells with high mitosis. The tumor cells of the cartilage areas were located in basophilic cartilaginous matrix. Intercellular matrix in the cartilaginous areas was stained blue with Masson's trichrome and deep blue with alcian blue, respectively. Immunohistochemically, the cartilaginous tumor cells demonstrated positive reactions for vimentin and S-100, and surrounding mesenchymal tumor cells are immunopositive for vimentin. This case was diagnosed as splenic extraskeletal mesenchymal chondrosarcoma of a Yorkshire Terrier dog, a toy breed.

Keywords

Acknowledgement

This research was supported by the 2023 education, research and student guidance grant funded by Jeju National University.

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