한국식품영양학회지 (The Korean Journal of Food And Nutrition)

  • 제36권6호
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  • Pages.462-470
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  • 2023
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  • 1225-4339(pISSN)
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  • 2287-4992(eISSN)
한국식품영양학회 (The Korean Society of Food and Nutrition)
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생식의 섭취가 흰쥐의 혈당 및 혈당 관련 지표에 미치는 영향

Effects of Saengshik on Blood Glucose-Related Biomarkers in Sprague-Dawley Rats

  • 남동훈 ((주)이롬 생명과학연구원) ;
  • 홍성길 ((주)이롬 이노파크) ;
  • 장혜은 ((주)이롬 생명과학연구원) ;
  • 권영인 (한남대학교 식품영양학과) ;
  • 문민선 ((주)이롬 생명과학연구원)
  • 투고 : 2023.09.25
  • 심사 : 2023.11.03
  • 발행 : 2023.12.31
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초록

The aim of this study was to investigate the hypoglycemic effects of saengshik in Sprague-Dawley (SD) rats and to explore the potential of three commercially available saengshik products (BS, LS, WS) as an alternative diabetic meal. Blood glucose levels were measured at 30, 60, 90, 120, and 150 minutes after the ingestion of experimental materials. In experiment 1, the amount of experimental materials remained the same. We measured blood glucose-related biomarkers as the area under the blood glucose response curve (AUC), glycemic index (GI), maximum concentration (Cmax), and time to reach maximum concentration (Tmax). AUC and Cmax of the experimental group showed significant differences compared to the control group, while GI and Tmax did not show significant differences among the groups but were lower in the experimental group compared to the control group. In experiment 2, carbohydrates were adjusted to the same amount. We measured blood glucose-related biomarkers in the same manner as Experiment 1 and obtained similar results. These hypoglycemic effects appear to be attributed to phytochemicals and dietary fiber found in whole, unrefined grains. These results suggest that saengshik exerts hypoglycemic effects by modulation of glucose-related biomarkers.

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