Annals of Clinical Neurophysiology

  • 제24권2호
  • /
  • Pages.84-89
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  • 2022
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  • 2508-691X(pISSN)
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  • 2508-6960(eISSN)
대한임상신경생리학회 (The Korean Society of Clinical Neurophysiology)
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Anterior canal-sparing bilateral vestibulopathy in MELAS syndrome

  • Kim, Jae-Myung (Department of Neurology, Chonnam National University Hospital, Chonnam National University Medical School) ;
  • Nam, Tai-Seung (Department of Neurology, Chonnam National University Hospital, Chonnam National University Medical School) ;
  • Lee, Seung-Han (Department of Neurology, Chonnam National University Hospital, Chonnam National University Medical School)
  • 투고 : 2022.07.18
  • 심사 : 2022.08.11
  • 발행 : 2022.10.30
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초록

Vestibular dysfunction has rarely been reported in MELAS syndrome. A 40-year-old male with long-term diabetes and hearing loss experienced a stroke-like episode with hemisensory disturbance and lactic acidosis. Brain MRI showed temporo-parieto-occipital cortical lesions, and a final diagnosis was made of MELAS syndrome with the mitochondrial 3243A>G mutation. Neuro-otologic evaluations revealed anterior-canal-sparing bilateral impairments of the vestibulo-ocular reflex in the video head impulse test and no caloric paresis. This unique pattern of vestibular dysfunction may aid in diagnosing MELAS syndrome.

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과제정보

This study was performed in accordance with the recommendations of the Institutional Review Board of the Chonnam National University Hospital (Gwangju, South Korea).

참고문헌

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