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Impact of the geometric properties of intracranial vascular bifurcation and the mechanism of aneurysm occurrence and rupture

  • Liu, Jun (The Second Affiliated Hospital, Wannan Medical College) ;
  • Zhang, Qingyun (Ma An Shan General Hospital of Ranger-Duree Healthcare) ;
  • Chen, Hua (The First Affiliated Hospital, Nanjing Medical University)
  • Received : 2021.09.04
  • Accepted : 2022.06.27
  • Published : 2022.10.25

Abstract

One factor that can heighten the risk of the rapture intracranial aneurysm (IA) is bifurcations, which can cause the IA to evaluate. This study presents the effect of geometric of intracranial vascular on the bifurcation analysis of the aneurysm occurrence. The aneurysm mechanism is mathematically modeled based on the nano pipe structures under the thermal stresses, and the impact of the aneurysm geometric on the stability and bifurcation points is analyzed. Because of the dimension of these structures, the classical theories could not predict their behavior perfectly, so the nonclassical and nonlocal theories are required for the mechanical modeling of the aneurysm. The presented results show that the bifurcation point of the aneurysm mechanism is dependent on the environment temperature, and the temperature change plays an essential role in the stability of these structures.

Keywords

Acknowledgement

This work was supported by 2021 key scientific research project of Anhui Provincial Health Commission, research on geometric characteristics of intracranial vascular bifurcation and mechanism of aneurysm occurrence and rupture, AHWJ2021a038; and 2022 Talent Fund of Peak Climbing Program of the Second Affiliated Hospital of Wannan Medical College (DFJH2022006) and the university-level scientific research Fund of Wannan Medical College in 2020 (WK2020ZF24).

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