International Journal of Stem Cells

  • 제15권2호
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  • Pages.113-121
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  • 2022
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  • 2005-3606(pISSN)
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  • 2005-5447(eISSN)
한국줄기세포학회 (Korean Society for Stem Cell Research)
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In Vivo Generation of Organs by Blastocyst Complementation: Advances and Challenges

  • Konstantina-Maria Founta (Department of Basic Science, Biomedical Research Foundation of the Academy of Athens) ;
  • Costis Papanayotou (Department of Basic Science, Biomedical Research Foundation of the Academy of Athens)
  • 투고 : 2021.07.01
  • 심사 : 2021.08.08
  • 발행 : 2022.05.30
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초록

The ultimate goal of regenerative medicine is to replace damaged cells, tissues or whole organs, in order to restore their proper function. Stem cell related technologies promise to generate transplants from the patients' own cells. Novel approaches such as blastocyst complementation combined with genome editing techniques open up new perspectives for organ replacement therapies. This review summarizes recent advances in the field and highlights the challenges that still remain to be addressed.

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참고문헌

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