Journal of Veterinary Science

The Korean Society of Veterinary Science (대한수의학회)
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Serial venous lactate measurement following gastrointestinal surgery in horses

  • Smanik, Lauren E. (Department of Clinical Sciences, Colorado State University) ;
  • Moser, Darla K. (Department of Clinical Sciences, Colorado State University) ;
  • Rothers, Kris P. (Department of Clinical Sciences, Colorado State University) ;
  • Hackett, Eileen S. (Department of Clinical Sciences, Colorado State University)
  • Received : 2022.02.08
  • Accepted : 2022.06.17
  • Published : 2022.09.30
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Abstract

Background: Prospective clinical study of blood lactate concentration in horses undergoing colic surgery is needed to determine utility in outcome prediction. Objectives: To evaluate venous lactate measurements in horses following colic surgery, including immediately after anesthetic recovery and daily throughout hospitalization, as well as to determine if lactate concentrations were significantly higher in horses that developed postoperative complications or did not survive to hospital discharge. Methods: Horses > 1 year of age undergoing surgery for colic and recovered from general anesthesia were sampled. A portable lactate meter was used to measure venous samples collected immediately following anesthetic recovery and daily throughout hospitalization. Complications arising during hospitalization and survival to hospital discharge were recorded. Results: Fifty one horses were enrolled, ranging in age from 2 to 29 years. Lactate concentration immediately following anesthetic recovery was higher in horses that developed complications during hospitalization (p = 0.046). The odds of developing complications postoperatively were doubled for horses with a venous lactate concentration > 5 mmol/L. Lactate measurements in non-survivors were significantly higher compared to survivors by 96 h postoperatively (p < 0.006). Conclusions: Higher venous lactate concentrations in the postoperative colic period were associated with an increased risk of complications and death. Results suggest horses with higher venous lactate measurements in recovery are more likely to have postoperative complications, with the odds of developing complications doubled for horses with a venous lactate > 5 mmol/L. Evaluation of venous lactate could provide information on prognosis in the postoperative period for horses with surgical colic.

Keywords

Acknowledgement

This study was provided by the Colorado State University Center for Companion Animal Studies and the Colorado State University Advances in Equine Health Fund.

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