Korean Journal of Veterinary Service (한국동물위생학회지)

The Korean Society of Veterinary Service (한국동물위생학회)
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Prevalence study of bovine viral diarrhea virus (BVDV) from cattle farms in Gyeongsangnam-do, South Korea in 2021

2021년 경남지역 소바이러스성설사 바이러스(BVDV) 감염실태 조사

  • Received : 2022.08.29
  • Accepted : 2022.09.17
  • Published : 2022.09.30
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Abstract

Bovine viral diarrhea (BVD) is one of the problematic wasting diseases in cattle leading to huge economic losses. This study was conducted to investigate the prevalence of BVD including transient and persistent infection from cattle farms in Gyeongsangnam-do. A total of 2,667 blood samples from 24 farms were collected and the sera were subjected to ELISA to detect BVD virus (BVDV) antigen, Erns. 5' untranslated region (5'-UTR) of BVDV-positive samples was sequenced to identify the genotype, and compared with isolates previously reported elsewhere. There were fourteen BVDV-positive calves from 2,667 samples (positive rate: 0.52%) from first ELISA testing followed by eight persistently infected out of eleven BVDV-positive samples (72.73%) in secondary ELISA that was conducted in at least four weeks suggesting the circulation of BVDV in the area. Sequencing analysis exhibited that thirteen BVDV-positive samples were identified as BVDV-1b and one sample was BVDV-2a. Phylogenetic analysis revealed that the BVDV-1b-positive samples showed the highest homology in nucleotide sequence to Korean isolates collected from Sancheong, Gyeongsangnam-do, while the BVDV-2a-positive sample (21GN7) was more similar to reference strains collected outside South Korea. This study will provide the recent fundamental data on BVD prevalence in Gyeongsangnam-do to be referred in developing strategies to prevent BVDV in South Korea.

Keywords

Acknowledgement

본 연구는 2021년도 경상남도 동물위생시험소 연구사업과 환경부 야생동물질병 전문인력 양성 특성화대학원 사업의 지원에 의해 수행되었다.

References

  1. Baker JC. 1995. The clinical manifestations of bovine viral diarrhea infection. Vet Clin North Am - Food Anim Pract 11: 425-445. https://doi.org/10.1016/S0749-0720(15)30460-6
  2. Barlow RM, Nettleton PF, Gardiner AC, Greig A., Campbell JR, Bonn JM. 1986. Persistent bovine virus diarrhoea virus infection in a bull. Vet Rec 118: 321-324. https://doi.org/10.1136/vr.118.12.321
  3. Brock KV. 2003. The persistence of bovine viral diarrhea virus. Biologicals 31: 133-135. https://doi.org/10.1016/S1045-1056(03)00029-0
  4. Chang L, Qi Y, Liu D, Du Q, Zhao X, Tong D. 2021. Molecular detection and genotyping of bovine viral diarrhea virus in Western China. BMC Vet Res 17: 1-7. https://doi.org/10.1186/s12917-020-02730-8
  5. Chi J, VanLeeuwen JA, Weersink A, Keefe GP. 2002. Direct production losses and treatment costs from bovine viral diarrhoea virus, bovine leukosis virus, Mycobacterium avium subspecies paratuberculosis, and Neospora caninum. Prev Vet Med 55: 137-153. https://doi.org/10.1016/S0167-5877(02)00094-6
  6. Cho JS, Kim GD, Park HJ, Lim YS, Hong SH, Seo CW, Ryu HJ, Sin RJ. 2013. Prevalence for persistently infected cattle with bovine viral diarrhea virus in Korea. Korean J Vet Serv 36: 105-110. https://doi.org/10.7853/KJVS.2013.36.2.105
  7. Choi KS, Song MC. 2011. Epidemiological observations of bovine viral diarrhea virus in Korean indigenous calves. Virus Genes 42: 64-70. https://doi.org/10.1007/s11262-010-0542-z
  8. Choi KS. 2011. Pathobiological Analysis of Bovine Viral Diarrhea Virus Identified in the Republic of Korea, J. Vet. Clin 28: 287-290.
  9. de Oliveira PSB, Silva Junior JVJ, Weiblen R, Flores EF. 2021. Subtyping bovine viral diarrhea virus (BVDV): Which viral gene to choose? Infect Genet Evol 92: 104891 https://doi.org/10.1016/j.meegid.2021.104891
  10. Decaro N. 2020. HoBi-Like Pestivirus and Reproductive Disorders. Front Vet Sci 7: 1-5. https://doi.org/10.3389/fvets.2020.00001
  11. Gomez-Romero N, Ridpath JF, Basurto-Alcantara FJ, Verdugo-Rodriguez A. 2021. Bovine Viral Diarrhea Virus in Cattle From Mexico: Current Status. Front Vet Sci 8: 1-8.
  12. Grooms DL. 2004. Reproductive consequences of infection with bovine viral diarrhea virus. Vet Clin North Am - Food Anim Pract 20: 5-19. https://doi.org/10.1016/j.cvfa.2003.11.006
  13. Gunn GJ, Stott AW, Humphry RW. 2004. Modelling and costing BVD outbreaks in beef herds. Vet J 167: 143-149. https://doi.org/10.1016/S1090-0233(03)00112-6
  14. Han DG, Ryu JH, Park J, Choi KS. 2018. Identification of a new bovine viral diarrhea virus subtype in the Republic of Korea. BMC Vet Res 14: 1-7. https://doi.org/10.1186/s12917-017-1323-x
  15. Houe H. 1999. Epidemiological features and economical importance of bovine virus diarrhoea virus (BVDV) infections. Vet Microbiol 64: 89-107. https://doi.org/10.1016/S0378-1135(98)00262-4
  16. Joo SK, Lim SI, Jeoung HY, Song JY, Oem JK, Mun SH, An DJ. 2013. Genome Sequence of Bovine Viral Diarrhea Virus Strain 10JJ-SKR, Belonging to Genotype 1d. Genome Announc 1: e00565-13.
  17. Khodakaram-Tafti A, Farjanikish GH. 2017. Persistent bovine viral diarrhea virus (BVDV) infection in cattle herds. Iran J Vet Res 18: 154-163.
  18. Kim YS, Kim YK, Lee SY, Lee KK, Lee KH, Song JC, Oem JK. 2019. Identification of Korean native cattle persistently infected with BVDV using Ear-notch method, Korean J Vet Serv 42: 117-120. https://doi.org/10.7853/KJVS.2019.42.2.117
  19. Kimura M. 1980. A simple method for estimating evolutionary rates of base substitutions through comparative studies of nucleotide sequences. J Mol Evol 16: 111-120. https://doi.org/10.1007/BF01731581
  20. Lanyon SR, Hill FI, Reichel MP, Brownlie J. 2014. Bovine viral diarrhoea: Pathogenesis and diagnosis. Vet J 199: 201-209. https://doi.org/10.1016/j.tvjl.2013.07.024
  21. Larska M, Polak MP, Riitho V, Strong R, Belak S, Alenius S, Uttenthal A, Liu L. 2012. Kinetics of single and dual infection of calves with an Asian atypical bovine pestivirus and a highly virulent strain of bovine viral diarrhoea virus 1. Comp Immunol Microbiol Infect Dis 35: 381-390. https://doi.org/10.1016/j.cimid.2012.03.003
  22. Larson RL, Pierce VL, Grotelueschen DM, Wittum TE. 2002. Economic evaluation of beef cowherd screening for cattle persistently-infected with bovine viral diarrhea virus. Bov Pr 36: 106-112.
  23. Lee HG, Cho A, Oh S, Roh J, Jung YH. 2020. A ten-year retrospective study of bovine infectious disease agents occurred in Korea from 2010 to 2019. Korean J Vet Serv 43: 113-128. https://doi.org/10.7853/KJVS.2020.43.3.113
  24. Moon SL, Blackinton JG, Anderson JR, Dozier MK, Dodd BJT, Keene JD, Wilusz CJ, Bradrick SS, Wilusz J. 2015. XRN1 stalling in the 5'UTR of Hepatitis C virus and Bovine Viral Diarrhea virus is associated with dysregulated host mRNA stability. PLoS Pathog 11: 1-21.
  25. Neill JD. 2013. Molecular biology of bovine viral diarrhea virus. Biologicals 41: 2-7. https://doi.org/10.1016/j.biologicals.2012.07.002
  26. Oem JK, Hyun BH, Cha SH, Lee KK, Kim SH, Kim HR, Park CK, Joo YS. 2009. Phylogenetic analysis and characterization of Korean bovine viral diarrhea viruses. Vet Microbiol 139: 356-360. https://doi.org/10.1016/j.vetmic.2009.06.017
  27. Park JS, Park JK, Cho EJ, Kim EG, Lee JM, Kim DK, Son SK. 2013. Prevalence of bovine viral diarrhea virus from dairy cattle farms in Gyeongnam southern area, Korea. Korean J Vet Serv 36: 7-13. https://doi.org/10.7853/KJVS.2013.36.1.7
  28. Park SJ, Jang EH, Sin YG, Jung SH, Moon GH, Cho SY, Cho SR. 2020. Prevalence of antigens to bovine viral diarrhea virus(BVDV) of cattle farms in Gyeongnam central area, Korea. 2020년도 경남 동물위생시험 소 사업연보: 130-139.
  29. Revell SG, Chasey D, Drew TW, Edwards S. 1988. Some observations on the semen of bulls persistently infected with bovine virus diarrhoea virus. The Veterinary Record 123: 122-125. https://doi.org/10.1136/vr.123.5.122
  30. Ryu JH, Choi KS. 2019. Genetic analysis of bovine viral diarrhea virus in pre-weaned native Korean calves. Trop Anim Health Prod 51: 2085-2090. https://doi.org/10.1007/s11250-019-01882-6
  31. Scharnbock B, Roch FF, Richter V, Funke C, Firth CL, Obritzhauser W, Baumgartner W, Kasbohrer A, Pinior B. 2018. A meta-analysis of bovine viral diarrhoea virus (BVDV) prevalences in the global cattle population. Sci Rep 8: 1-15. https://doi.org/10.1038/s41598-017-17765-5
  32. Song MC, Choi KS. 2010. Genetic Characterization of Bovine Viral Diarrhea Virus from Korean Indig- enous Calves in Gyeongbuk Province. J Vet Clin 27: 220-224.
  33. Sozzi E, Righi C, Boldini M, Bazzucchi M, Pezzoni G, Gradassi M, Petrini S, Lelli D, Ventura G, Pierini I, Moreno A, Brocchi E, Lavazza A, de Mia GM. 2020. Cross-Reactivity Antibody Response after Vaccination with Modified Live and Killed Bovine Viral Diarrhoea Virus (BVD). Vaccines 8: 374. https://doi.org/10.3390/vaccines8030374
  34. Tamura K, Stecher G, Kumar S. 2021. MEGA11: Molecular Evolutionary Genetics Analysis Version 11. Mol Biol Evol 38: 3022-3027. https://doi.org/10.1093/molbev/msab120
  35. Walz PH, Chamorro MFM, Falkenberg S, Passler T, van der Meer F, R Woolums A. 2020. Bovine viral diarrhea virus: An updated American College of Veterinary Internal Medicine consensus statement with focus on virus biology, hosts, immunosuppression, and vaccination. J Vet Intern Med 34: 1690-1706. https://doi.org/10.1111/jvim.15816
  36. Yang DK, Kim BH, Kweon CH, Park JK, Kim HY, So BJ, Kim IJ. 2007. Genetic typing of Bovine Viral Diarrhea Viruses (BVDV) circulating in Korea. J Bacteriol Virol, 37: 147-152. https://doi.org/10.4167/jbv.2007.37.3.147
  37. Yesilbag K, Alpay G, Becher P. 2017. Variability and global distribution of subgenotypes of bovine viral diarrhea virus. Viruses 9: 128. https://doi.org/10.3390/v9060128