CELLMED (셀메드)

Cellmed Orthocellular Medicine and Pharmaceutical Association (셀메드 세포교정의약학회)
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Effect of Sharbat Afsantīn in Poly Cystic Ovarian Disease - An Open Observational Study

  • Zubair, Zainab (Dept. of Ilmul Qabalat wa Amraze Niswan, National Institute of Unani Medicine) ;
  • Shameem, Ismath (Dept. of Ilmul Qabalat wa Amraze Niswan, National Institute of Unani Medicine) ;
  • Begum, Wajeeha (Dept. of Ilmul Qabalat wa Amraze Niswan, National Institute of Unani Medicine)
  • Received : 2022.06.02
  • Accepted : 2022.08.24
  • Published : 2022.08.31
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Abstract

Objective: The objective of the study was to evaluate the effect of Sharbat Afsantin in Polycystic Ovarian Disease. Methods: An open observational study was carried out in the Department of Ilmul Qabalat wa Amraze Niswan. Diagnosed cases(n=30) of PCOD were included in the study. Patients with thyroid dysfunction, systemic diseases, on hormonal treatment in last three months, pregnancy and lactation were excluded. Research drug (Sharbat Afsantin) was administered orally in a dose of 25ml twice daily for 15 days/cycle for three consecutive cycles. Outcome measures were, changes in subjective parameters (duration of cycle, duration and amount of flow and weight reduction) and objective parameters {pictorial blood loss assessment chart (PBAC) score, basal metabolic index (BMI), modified Ferriman Gallwey (mFG) score, acanthosis nigricans scale and pelvic ultrasonography}. Data were analyzed using paired Student 't' test. Results: Changes in duration of cycle, duration and amount of flow were achieved in 83.3%, 50% and 40% patients respectively and weight reduction in 30% patients. Changes in PBAC score and BMI were achieved in 50% and 30% patients respectively and 30% patients showed normal findings on pelvic ultrasonography. Conclusion: Sharbat Afsantin can be used as an alternate remedy in PCOD patients, as it has significant effect to regularize menstruation by reduction in BMI and probably by improving insulin resistance in PCOD. No adverse effect of Sharbat Afsantin was noted during the trial.

Keywords

Acknowledgement

The authors are thankful to the Director, National Institute of Unani Medicine, Bengaluru for providing all facilities to complete the research and Dr. KP Suresh, Scientist (Biostatistics), National Institute of Veterinary Epidemiology and Disease Informatics (NIVEDI) for performing the statistical analysis.

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