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Antioxidative Activity of Solvent Fraction from Taraxacum officinale

민들레 용매분획물의 항산화 활성

  • Lee, Youn Ri (Dept. of Food and Nutrition, Daejeon Health Institute of Technology)
  • 이연리 (대전보건대학교 식품영양과)
  • Received : 2022.03.09
  • Accepted : 2022.07.29
  • Published : 2022.08.31

Abstract

Antioxidant activities and α-glucosidase inhibitory activities of Taraxacum officinale solvent fractions were measured. Extraction yields (relative to raw material) of 50% ethanol, hexane, ethyl acetate, butanol, and water were found to be 10.29, 2.61, 5.54, 2.15, and 0.96%, respectively. Polyphenol and flavonoid contents were high in ethyl acetate extract of Taraxacum officinale at 56.88 mg gallic acid/g and 33.27 mg gallic acid/g, respectively. DPPH, hydroxyl radical scavenging activity, and SOD-like activity measurement (IC50%) of Taraxacum officinale 50% ethanol extract, hexane, butanol, ethyl acetate, and water fractions were 22.64, 18.65, 10.29, 20.81, 20.46 mg/mL, 24.68, 10.69, respectively. It was found to be 9.66, 15.81, 13.77 mg/mL, 32.84, 17.09, 12.73, 33.63, and 33.91 mg/mL, and was high in the ethyl acetate layer. Results showed that α-glucosidase inhibitory activities of Taraxacum officinale solvent fraction were 25.75, 15.93, 35.87, 15.96, and 2.88% for 50% ethanol extract, hexane, butanol, ethyl acetate, and water fractions, respectively.

Keywords

References

  1. Albertazzi P, Steel SA, Clifford E, Bottazzi M. 2002. Attitudes towards and use of dietary supplementation in a sample of postmenopausal women. Climacteric 5:374-382 https://doi.org/10.1080/cmt.5.4.374.382
  2. Blois MS. 1958. Antioxidant determinations by the use of a stable free radical. Nature 181:1199-1200 https://doi.org/10.1038/1811199a0
  3. Branen AL. 1975. Toxicology and biochemistry of butylated hydroxyanisole and butylated hydroxytoluene. J Am Oil Chem Soc 52:59-63 https://doi.org/10.1007/BF02901825
  4. Choi MH, Kim KH, Yook HS. 2019. Antioxidant and antibacterial activity of premature mandarin. J Korean Soc Food Sci Nutr 48:622-629 https://doi.org/10.3746/jkfn.2019.48.6.622
  5. Choi YJ, Park HS, Lee JS, Park KS, Park SS, Jung IC. 2015. Changes in physicochemical properties of pork patty with dandelion extract during refrigerated storage. Korean J Food Cookery Sci 31:423-430 https://doi.org/10.9724/kfcs.2015.31.4.423
  6. Dewanto V, Wu X, Liu RH. 2002. Processed sweet corn has higher antioxidant activity. J Agric Food Chem 50: 4959-4964 https://doi.org/10.1021/jf0255937
  7. Dias MI, Barros L, Alves RC, Oliveira MBPP, Santos-Buelga C, Ferreira ICFR. 2014. Nutritional composition, antioxidant activity and phenolic compounds of wild Taraxacum sect. Ruderalia. Food Res Int 56:266-271 https://doi.org/10.1016/j.foodres.2014.01.003
  8. Ding JL, Lim IJ, Lee HD, Cha WS. 2006. Analysis of minerals, amino acids, and vitamin of Lespedeza cuneata. Korean J Biotechnol Bioeng 21:414-417
  9. Heo SI, Wang MH. 2008. Antioxidant activity and cytotoxicity effect of extracts from Taraxacum mongolicum H. Korean J Pharmacogn 39:255-259
  10. Kalt W, Hanneken A, Milbury P, Tremblay F. 2010. Recent research on polyphenolics in vision and eye health. J Agric Food Chem 58:4001-4007 https://doi.org/10.1021/jf903038r
  11. Kang MJ, Kim KS. 2001. Current trends of research and biological activities of dandelion. Food Ind Nutr 6:60-67
  12. Kang MJ, Seo YH, Kim JB, Shin S, Kim K. 2000. The chemical composition of Taraxacum officinale consumed in Korea. Korean J Soc Food Sci 16:182-187
  13. Kim TJ. 1994. Our Flower, 100 Species. 9th ed. pp.2-5. Hyunamsa
  14. Kim YC, Rho JH, Kim KT, Cho CW, Rhee YK, Choi UK. 2008. Phenolic acid contents and ROS scavenging activity of dandelion (Taraxacum officinale). Korean J Food Preserv 15:325-331
  15. Kitani K, Minami C, Yamamoto T, Kanai S, Ivy GO, Carrillo MC. 2002. Pharmacological interventions in aging and age-associated disorders: Potentials of propargylamines for human use. Ann NY Acad Sci 959:295-307 https://doi.org/10.1111/j.1749-6632.2002.tb02101.x
  16. Lee HH, Kim YS, Park HY. 2007. Plant regeneration via organogenesis from leaf explant culture of Taraxacum coreanum Nakai. Korean J Med Crop Sci 15:62-66
  17. Lee NH, Hong JI, Kim JY, Chiang MH. 2009. Antioxidant properties and protective effects of Inula britannica var. chinensis Regel on oxidative stress-induced neuronal cell damage. Korean J Food Sci Technol 41:87-92
  18. Lee SY, Shin YJ, Park JH, Kim SM, Park CS. 2008. An analysis of the Gyungokgo's ingredients and a comparison study on anti-oxidation effects according to the kinds of extract. Korean J Herbol 23:123-136
  19. Lim AK, Kim JO, Jung MJ, Jung HK, Hong JH, Kim DI. 2008. Functional biological activity of hot water and ethanol extracts from Taraxaci herba. J Korean Soc Food Sci Nutr 37:1231-1237 https://doi.org/10.3746/JKFN.2008.37.10.1231
  20. Loguercio C, Festi D. 2011. Silybin and the liver: From basic research to clinical practice. World J Gastroenterol 17:2288-2301 https://doi.org/10.3748/wjg.v17.i18.2288
  21. Manian R, Anusuya N, Siddhuraju P, Manian S. 2008. The antioxidant activity and free radical scavenging potential of two different solvent extracts of Camellia sinensis (L.) O. Kuntz, Ficus bengalensis L. and Ficus racemosa L. Food Chem 107:1000-1007 https://doi.org/10.1016/j.foodchem.2007.09.008
  22. Marklund S, Marklund G. 1974. Involvement of the superoxide anion radical in the autoxidation of pyrogallol and a convenient assay for superoxide dismutase. Eur J Biochem 47:469-474 https://doi.org/10.1111/j.1432-1033.1974.tb03714.x
  23. Masaki H, Sakaki S, Atsumi T, Sakurai H. 1995. Active-oxygen scavenging activity of plant extracts. Biol Pharm Bull 18:162-166 https://doi.org/10.1248/bpb.18.162
  24. Middleton E Jr, Kandaswami C. 1994. Potential health-promoting properties of citrus flavonoids. Food Technol 48:115-119
  25. Moon JS, Kim SJ, Park YM, Hwang IS, Kim EH, Park JW, Park IB, Kim SW, Kang SG, Park YK, Jung ST. 2004. Antimicrobial effect of methanol extracts from some medicinal herbs and the content of phenolic compounds. Korean J Food Preserv 11:207-213
  26. Ryu SH, Jeon YS, Kwon MJ, Moon JW, Lee YS, Moon GS. 1997. Effect of kimchi extracts to reactive oxygen species in skin cell cytotoxicity. J Korean Soc Food Sci Nutr 26:814-821
  27. Smirnoff N, Cumbes QJ. 1989. Hydroxyl radical scavenging activity of compatible solutes. Phytochemistry 28:1057-1060 https://doi.org/10.1016/0031-9422(89)80182-7
  28. Tibbot BK, Skadsen RW. 1996. Molecular cloning and characterization of a gibberellin-inducible, putative α-glucosidase gene from barley. Plant Mol Biol 30:229-241 https://doi.org/10.1007/BF00020110
  29. Williams CA, Goldstone F, Greenham J. 1996. Flavonoids, cinnamic acids and coumarins from the different tissues and medicinal preparations of Taraxacum officinale. Phytochemistry 42:121-127 https://doi.org/10.1016/0031-9422(95)00865-9