Clinical Endoscopy

The Korean Society of Gastrointestinal Endoscopy (대한소화기내시경학회)
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Development of colon cancer in a patient with longstanding colonic diffuse ganglioneuromatosis: a case report

  • Jin Sun Oh (Department of Internal Medicine, Hoengseong Daeseong Hospital) ;
  • Seung Wook Hong (Department of Gastroenterology, Asan Medical Center, University of Ulsan College of Medicine) ;
  • Jin Hee Noh (Department of Gastroenterology, Asan Medical Center, University of Ulsan College of Medicine) ;
  • Jiyoung Yoon (Department of Gastroenterology, Asan Medical Center, University of Ulsan College of Medicine) ;
  • Hyo Jeong Kang (Department of Pathology, Asan Medical Center, University of Ulsan College of Medicine) ;
  • Young Soo Park (Department of Pathology, Asan Medical Center, University of Ulsan College of Medicine) ;
  • Dong-Hoon Yang (Department of Gastroenterology, Asan Medical Center, University of Ulsan College of Medicine) ;
  • Jeong-Sik Byeon (Department of Gastroenterology, Asan Medical Center, University of Ulsan College of Medicine)
  • Received : 2020.11.26
  • Accepted : 2021.01.04
  • Published : 2022.05.30
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Abstract

Colonic diffuse ganglioneuromatosis is an extremely rare disease in which multiple tumors derived from the ganglion cells, nerve fibers, and supporting cells are distributed in the colon. It is generally considered to be a benign neoplastic condition and is occasionally associated with rare hereditary conditions such as neurofibromatosis type I or multiple endocrine neoplasia type 2B. Here, we report a case of a patient in whom colon cancer developed 12 years after the initial diagnosis of colonic diffuse ganglioneuromatosis, which suggests a possible association between colonic diffuse ganglioneuromatosis and colorectal cancer.

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References

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