Clinical Endoscopy

  • 제55권2호
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  • Pages.248-255
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  • 2022
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  • 2234-2400(pISSN)
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  • 2234-2443(eISSN)
대한소화기내시경학회 (The Korean Society of Gastrointestinal Endoscopy)
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Efficacy and Safety of Endoscopic Submucosal Dissection for Superficial Gastric Neoplasms: A Latin American Cohort Study

  • Fernando Palacios-Salas (Clinica Delgado y Oncosalud - AUNA) ;
  • Harold Benites-Goni (Vicerrectorado de Investigacion, Universidad San Ignacio de Loyola) ;
  • Luis Marin-Calderon (Hospital Nacional Edgardo Rebagliati Martins) ;
  • Paulo Bardalez-Cruz (Hospital Nacional Edgardo Rebagliati Martins) ;
  • Jorge Vasquez-Quiroga (Hospital Nacional Edgardo Rebagliati Martins) ;
  • Edgar Alva-Alva (Hospital Nacional Edgardo Rebagliati Martins) ;
  • Bryan Medina-Morales (Hospital Nacional Edgardo Rebagliati Martins) ;
  • Jairo Asencios-Cusihuallpa (Hospital Nacional Edgardo Rebagliati Martins)
  • 투고 : 2021.06.17
  • 심사 : 2021.07.22
  • 발행 : 2022.03.30
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초록

Background/Aims: Endoscopic submucosal dissection (ESD) is the preferred technique for treating early gastric cancer (EGC). However, very few studies have been conducted in South America. This study aimed to assess the efficacy and safety of ESD for EGC. Methods: We analyzed data from a prospective cohort from 2013 to 2020. A total of 152 superficial gastric neoplasms that fulfilled the absolute or expanded criteria for ESD were included. Outcomes were en bloc, R0, and curative resection rates, incidence of adverse events, and length of procedure. Results: The age of the enrolled patients was 68.4±11.3 years. The number of included patients based on the absolute and expanded indications was 150 and 2, respectively. En bloc, R0, and curative resections were achieved in 98.0%, 96.1%, and 89.5% of the cases, respectively. Bleeding and perforation were reported in 5.9% and 6.6% of the cases, respectively. Histopathological examination revealed low-grade dysplasia, high-grade dysplasia, well-differentiated adenocarcinoma, and poorly differentiated adenocarcinoma in 13, 20, 117, and 2 cases, respectively. Conclusions: Our study shows that ESD performed by properly trained endoscopists in reference centers is safe and effective, with comparable therapeutic outcomes to those reported in the Eastern series.

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참고문헌

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