Journal of Plant Biotechnology

The Korean Society of Plant Biotechnology (한국식물생명공학회)
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Botanical features and ethnopharmacological potential of Leonotis nepetifolia (L.) R. Br: a review

  • Gang, Roggers (University of Science & Technology (UST), Korean Convergence Medicine) ;
  • Kang, Youngmin (University of Science & Technology (UST), Korean Convergence Medicine)
  • Received : 2021.11.06
  • Accepted : 2022.01.07
  • Published : 2022.03.31
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Abstract

Leonotis nepetifolia (L.) R. Br, commonly called dagga, klip dagga, or lion's ear, has been used to effectively treat various diseases and other health problems for a long time because of its antimicrobial, anti-inflammatory, antioxidant, and analgesic activities. Several studies have attributed these biological activities to L. nepetifolia's constituent secondary metabolites, such as alkaloids, phenolics, flavonoids, tannins, steroids, glycosides, coumarins, anthocyanins, and saponins. This review aims to examine the evidence-based ethnopharmacological uses of L. nepetifolia in the treatment of bronchial asthma, diarrhea, skin diseases, malaria, burns, cancer, diabetes mellitus, and rheumatism. However, although L. nepetifolia has great potential to treat these diseases, further isolation and identification of its therapeutic phytochemical constituents are required. In addition, the performance of its extracts and phytochemicals should be thoroughly tested in preclinical and clinical trials in order to ascertain their safety and efficacy, which will prove valuable in developing new medicines.

Keywords

Acknowledgement

This research was funded by Development of Sustainable Application for Standard Herbal Resources (KSN2013320), Korea Institute of Oriental Medicine through the Ministry of Science and ICT, Republic of Korea.

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