Fisheries and Aquatic Sciences

The Korean Society of Fisheries and Aquatic Science (한국수산과학회)
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In vitro screening of extracts from 38 marine animal resources for novel cosmeceutical activities

  • Im, Seung Tae (Department of Medical Science, Soonchunhyang University) ;
  • Jang, Yebin (Department of Medical Science, Soonchunhyang University) ;
  • Park, Subin (Department of Medical Science, Soonchunhyang University) ;
  • Mun, Haeun (Department of Medical Science, Soonchunhyang University) ;
  • Kim, Dong Sam (Samcheok Prasiola Japonica Research Center, Samcheok City Hall) ;
  • Lee, Dae-Sung (National Marine Biodiversity Institute of Korea) ;
  • Lee, Jeong-Min (National Marine Biodiversity Institute of Korea) ;
  • Yim, Mi-Jin (National Marine Biodiversity Institute of Korea) ;
  • Kim, Ji-Yul (National Marine Biodiversity Institute of Korea) ;
  • Kim, Hyun-Soo (National Marine Biodiversity Institute of Korea) ;
  • Ko, Seok-Chun (National Marine Biodiversity Institute of Korea) ;
  • Jung, Won-Kyo (Department of Biomedical Engineering and New-Senior Healthcare Innovation Center (BK21 Plus), Pukyong National University) ;
  • Lee, Seung-Hong (Department of Medical Science, Soonchunhyang University)
  • Received : 2022.04.14
  • Accepted : 2022.05.29
  • Published : 2022.06.30
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Abstract

Marine resources have various biological activities and their constituents are more novel than those of land organisms. Several biologically active constituents have been found in marine organisms. Recently, many studies have reported that marine animals (MAs) can be used as functional ingredients in functional foods or nutraceutical due to their health benefits. However, no studies have extensively investigated the cosmeceutical activities of MAs extracts. Here, 70% ethanol extracts of 38 MAs were investigated for their activities of whitening and anti-aging properties for use as materials in novel cosmeceuticals. Anti-aging activities were determined by skin aging-related enzyme activities (anti-collagenase, anti-elastase, anti-hyaluronidase) and whitening activities (anti-tyrosinase, anti-3,4-dihydroxyl-L-phenylalanine [DOPA] oxidation) evaluated by colorimetric method. Among the 38 MAs, we found that Urechis unicinctus and Petrosia corticata extracts showed the strongest inhibitory effects against tyrosinase and DOPA oxidation, respectively. Our results additionally showed that Protankyra bidentata extract might provide a major source of anti-hyaluronidase and anti-elastase; meanwhile, anti-collagenase effects were similar in most MAs. Overall, these results suggest that extracts of marine animals have potential as a tyrosinase, collagenase, elastase, and hyaluronidase inhibitors. Taken together, MA resources could be considered as a novel cosmeceutical agent to be applied in cosmetic industry.

Keywords

Acknowledgement

This research was supported by Basic Science Research Program through the National Research Foundation of Korea (NRF) funded by the Ministry of Education (2021R1A6A1A03039211) and was supported by the Soonchunhyang University Research Fund.

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