Journal of Periodontal and Implant Science

Korean Academy of Periodontology (대한치주과학회)
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Retrospective analysis of the effects of non-communicable diseases on periodontitis treatment outcomes

  • Kim, Eun-Kyung (Department of Periodontology, Dental Research Institute, Pusan National University Dental Hospital) ;
  • Kim, Hyun-Joo (Department of Periodontology, Dental Research Institute, Pusan National University Dental Hospital) ;
  • Lee, Ju-Youn (Department of Periodontology, Dental Research Institute, Pusan National University Dental Hospital) ;
  • Park, Hae-Ryoun (Periodontal Disease Signaling Network Research Center, Dental and Life Science Institute, Pusan National University School of Dentistry) ;
  • Cho, Youngseuk (Department of Statistics, Pusan National University) ;
  • Noh, Yunhwan (Department of Statistics, Pusan National University) ;
  • Joo, Ji-Young (Department of Periodontology, Dental Research Institute, Pusan National University Dental Hospital)
  • Received : 2021.07.08
  • Accepted : 2021.10.25
  • Published : 2022.06.30
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Abstract

Purpose: We retrospectively analysed patients' dental and periodontal status according to the presence of non-communicable diseases (NCDs) and the effects of NCDs on periodontal treatment outcomes. Factors influencing disease recurrence were investigated using decision tree analysis. Methods: We analysed the records of patients who visited the Department of Periodontology, Pusan National University Dental Hospital from June 2014 to October 2019. As baseline subjects, 1,362 patients with periodontitis and who underwent full-mouth periodontal examinations before periodontal treatment were selected. Among them, 321 patients who underwent periodontal examinations after the completion of periodontal treatment and 143 who continued to participate in regular maintenance were followed-up. Results: Forty-three percent of patients had a NCD. Patients without NCDs had more residual teeth and lower sum of the number of total decayed, missing, filled teeths (DMFT) scores. There was no difference in periodontal status according to NCD status. Patients with a NCD showed significant changes in the plaque index after periodontal treatment. The decision tree model analysis demonstrated that osteoporosis affected the recurrence of periodontitis. Conclusions: The number of residual teeth and DMFT index differed according to the presence of NCDs. Patients with osteoporosis require particular attention to prevent periodontitis recurrence.

Keywords

Acknowledgement

This study was supported by a National Research Foundation of Korea (NRF; Daejeon, Korea) grant funded by the Korean government (MSIT) (grant No. NRF-2018R1A5A2023879).

References

  1. Bourgeois D, Inquimbert C, Ottolenghi L, Carrouel F. Periodontal pathogens as risk factors of cardiovascular diseases, diabetes, rheumatoid arthritis, cancer, and chronic obstructive pulmonary disease-Is there cause for consideration? Microorganisms 2019;7:424. https://doi.org/10.3390/microorganisms7100424
  2. Lee JH, Oh JY, Youk TM, Jeong SN, Kim YT, Choi SH. Association between periodontal disease and noncommunicable diseases: a 12-year longitudinal health-examinee cohort study in South Korea. Medicine (Baltimore) 2017;96:e7398. https://doi.org/10.1097/md.0000000000007398
  3. World Health Organization. WHO global status report on noncommunicable diseases 2014. Geneva: WHO; 2014.
  4. Lee JH, Lee JS, Park JY, Choi JK, Kim DW, Kim YT, et al. Association of lifestyle-related comorbidities with periodontitis: a nationawide cohort study in Korea. Medicine (Baltimore) 2015;94:e1567. https://doi.org/10.1097/MD.0000000000001567
  5. Watt RG, Sheiham A. Integrating the common risk factor approach into a social determinants framework. Community Dent Oral Epidemiol 2012;40:289-96. https://doi.org/10.1111/j.1600-0528.2012.00680.x
  6. Kassier SM. Periodontal disease and non-communicable diseases. Strength of bidirectional associations. SADJ 2016;71:404-9.
  7. Bartold PM, Van Dyke TE. Host modulation: controlling the inflammation to control the infection. Periodontol 2000 2017;75:317-29. https://doi.org/10.1111/prd.12169
  8. Che D, Liu Q, Rasheed K, Tao X. Decision tree and ensemble learning algorithms with their applications in bioinformatics. Adv Exp Med Biol 2011;696:191-9. https://doi.org/10.1007/978-1-4419-7046-6_19
  9. Schenkein HA, Loos BG. Inflammatory mechanisms linking periodontal diseases to cardiovascular diseases. J Periodontol 2013;84:S51-69. https://doi.org/10.1902/jop.2013.134006
  10. Janakiram C, Taha F, Joseph J, Ramanarayanan V. Assessment of common risk factors between oral diseases and non-communicable diseases in a hospital-based population in Kerala, India-a cross-sectional study. J Clin Diagn Res 2019;13:16-20.
  11. Genco RJ, Borgnakke WS. Diabetes as a potential risk for periodontitis: association studies. Periodontol 2000 2020;83:40-5. https://doi.org/10.1111/prd.12270
  12. Martinez-Herrera M, Lopez-Domenech S, Silvestre FJ, Silvestre-Rangil J, Banuls C, Hernandez-Mijares A, et al. Dietary therapy and non-surgical periodontal treatment in obese patients with chronic periodontitis. J Clin Periodontol 2018;45:1448-57. https://doi.org/10.1111/jcpe.13030
  13. Health Insurance Review & Assessment Service (KR). 2019 national health insurance statistical yearbook [Internet]. Wonju: HIRA; 2020 [cited 2020 Oct]. Available from: https://www.hira.or.kr/bbsDummy.do?pgmid=HIRAA020045020000&brdScnBltNo=4&brdBltNo=2312&pageIndex=1#none.
  14. Kim DH, Jeong SN, Lee JH. Severe periodontitis with tooth loss as a modifiable risk factor for the development of Alzheimer, vascular, and mixed dementia: National Health Insurance Service-National Health Screening Retrospective Cohort 2002-2015. J Periodontal Implant Sci 2020;50:303-12. https://doi.org/10.5051/jpis.2000600030
  15. Lee HJ, Choi EK, Park JB, Han KD, Oh S. Tooth loss predicts myocardial infarction, heart failure, stroke, and death. J Dent Res 2019;98:164-70. https://doi.org/10.1177/0022034518814829
  16. Brito F, de Barros FC, Zaltman C, Carvalho AT, Carneiro AJ, Fischer RG, et al. Prevalence of periodontitis and DMFT index in patients with Crohn's disease and ulcerative colitis. J Clin Periodontol 2008;35:555-60. https://doi.org/10.1111/j.1600-051X.2008.01231.x
  17. Costa FO, Miranda Cota LO, Pereira Lages EJ, Soares Dutra Oliveira AM, Dutra Oliveira PA, Cyrino RM, et al. Progression of periodontitis and tooth loss associated with glycemic control in individuals undergoing periodontal maintenance therapy: a 5-year follow-up study. J Periodontol 2013;84:595-605. https://doi.org/10.1902/jop.2012.120255
  18. Tanaka MH, Bocardi K, Kishimoto KY, Jacques P, Spolidorio DM, Giro EM. DMFT index assessment and microbiological analysis of Streptococcus mutans in institutionalized patients with special needs. Braz J Oral Sci 2009;8:9-13.
  19. Holmlund A, Holm G, Lind L. Severity of periodontal disease and number of remaining teeth are related to the prevalence of myocardial infarction and hypertension in a study based on 4,254 subjects. J Periodontol 2006;77:1173-8. https://doi.org/10.1902/jop.2006.050233
  20. Sangwan A, Tewari S, Singh H, Sharma RK, Narula SC. Periodontal status and hyperlipidemia: statin users versus non-users. J Periodontol 2013;84:3-12. https://doi.org/10.1902/jop.2012.110756
  21. Teixeira FC, Marin-Leon L, Gomes EP, PedrAo AM, Pereira AD, Francisco PM. Relationship between periodontitis and subclinical risk indicators for chronic non-communicable diseases. Braz Oral Res 2020;34:e058. https://doi.org/10.1590/1807-3107bor-2020.vol34.0058
  22. Eickholz P, Kaltschmitt J, Berbig J, Reitmeir P, Pretzl B. Tooth loss after active periodontal therapy. 1: patient-related factors for risk, prognosis, and quality of outcome. J Clin Periodontol 2008;35:165-74. https://doi.org/10.1111/j.1600-051X.2007.01184.x
  23. Fardal O, Johannessen AC, Linden GJ. Tooth loss during maintenance following periodontal treatment in a periodontal practice in Norway. J Clin Periodontol 2004;31:550-5. https://doi.org/10.1111/j.1600-051X.2004.00519.x
  24. Matuliene G, Studer R, Lang NP, Schmidlin K, Pjetursson BE, Salvi GE, et al. Significance of Periodontal Risk Assessment in the recurrence of periodontitis and tooth loss. J Clin Periodontol 2010;37:191-9. https://doi.org/10.1111/j.1600-051X.2009.01508.x
  25. Lang NP, Tonetti MS. Periodontal risk assessment (PRA) for patients in supportive periodontal therapy (SPT). Oral Health Prev Dent 2003;1:7-16.
  26. Baumer A, El Sayed N, Kim TS, Reitmeir P, Eickholz P, Pretzl B. Patient-related risk factors for tooth loss in aggressive periodontitis after active periodontal therapy. J Clin Periodontol 2011;38:347-54. https://doi.org/10.1111/j.1600-051X.2011.01698.x
  27. Kribbs PJ. Comparison of mandibular bone in normal and osteoporotic women. J Prosthet Dent 1990;63:218-22. https://doi.org/10.1016/0022-3913(90)90108-O
  28. Kim JW, Kong KA, Kim HY, Lee HS, Kim SJ, Lee SH, et al. The association between bone mineral density and periodontitis in Korean adults (KNHANES 2008-2010). Oral Dis 2014;20:609-15. https://doi.org/10.1111/odi.12179
  29. Genco RJ, Borgnakke WS. Risk factors for periodontal disease. Periodontol 2000 2013;62:59-94. https://doi.org/10.1111/j.1600-0757.2012.00457.x
  30. Tezal M, Wactawski-Wende J, Grossi SG, Ho AW, Dunford R, Genco RJ. The relationship between bone mineral density and periodontitis in postmenopausal women. J Periodontol 2000;71:1492-8. https://doi.org/10.1902/jop.2000.71.9.1492