Archives of Obesity and Metabolism (비만대사연구학술지)

The Study of Obesity and Metabolic Syndrome, KAFM (대한가정의학회 비만대사증후군연구회)
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Obesity Paradox-Bias or Fact?

비만 역설-편향 혹은 실제

  • Kim, Bom Taeck (Department of Family Practice and Community Health, Ajou University School of Medicine (AUSOM))
  • 김범택 (아주대학교의과대학 가정의학교실)
  • Received : 2022.06.02
  • Accepted : 2022.06.16
  • Published : 2022.06.30
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Abstract

Although it has been confirmed that excessive body fat increases health risks and all-cause mortality, several epidemiological studies have reported that overweight or obesity in patients with chronic diseases and in older adults is advantageous with respect to mortality. Several mechanisms have been proposed to explain the biological basis of this obesity paradox. The marked heterogeneity of findings observed across studies and the possibility of systematic errors in these studies have cast doubt on the actual existence of the obesity paradox. However, the obesity paradox questioned the validity of body mass index as the best indicator for obesity in terms of predicting its comorbidities and urges clinicians to focus more on changes in body composition and related metabolic derangements, rather than body weight per se.

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References

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