Journal of Veterinary Science

  • 제23권4호
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  • Pages.57.1-57.9
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  • 2022
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  • 1229-845X(pISSN)
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  • 1976-555X(eISSN)
대한수의학회 (The Korean Society of Veterinary Science)
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Epidemiological investigation and phylogenetic analysis of Classical Swine Fever virus in Yunnan province from 2015 to 2021

  • Yao, Jun (Yunnan Tropical and Subtropical Animal Virus Diseases Laboratory, Yunnan Animal Science & Veterinary Institute) ;
  • Su, Linlin (College of Animal Medicine, Yunnan Agricultural University) ;
  • Wang, Qiaoping (College of Animal Medicine, Yunnan Agricultural University) ;
  • Gao, Lin (Yunnan Tropical and Subtropical Animal Virus Diseases Laboratory, Yunnan Animal Science & Veterinary Institute) ;
  • Xie, Jiarui (Yunnan Tropical and Subtropical Animal Virus Diseases Laboratory, Yunnan Animal Science & Veterinary Institute) ;
  • He, Yuwen (Yunnan Tropical and Subtropical Animal Virus Diseases Laboratory, Yunnan Animal Science & Veterinary Institute) ;
  • Shu, Xianghua (College of Animal Medicine, Yunnan Agricultural University) ;
  • Song, Chunlian (College of Animal Medicine, Yunnan Agricultural University) ;
  • Chai, Jun (College of Animal Medicine, Yunnan Agricultural University) ;
  • Zhang, Yifang (College of Animal Medicine, Yunnan Agricultural University) ;
  • Yang, Shibiao (Yunnan Tropical and Subtropical Animal Virus Diseases Laboratory, Yunnan Animal Science & Veterinary Institute)
  • 투고 : 2022.02.15
  • 심사 : 2022.05.13
  • 발행 : 2022.07.31
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초록

Background: Classical swine fever virus (CSFV), the causative agent of classical swine fever (CFS), is a highly contagious disease that poses a serious threat to Chinese pig populations. Objectives: Many provinces of China, such as Shandong, Henan, Hebei, Heilongjiang, and Liaoning provinces, have reported epidemics of CSFV, while the references to the epidemic of CSFV in Yunnan province are rare. This study examined the epidemic characteristics of the CSFV in Yunnan province. Methods: In this study, 326 tissue samples were collected from different regions in Yunnan province from 2015 to 2021. A reverse transcription-polymerase chain reaction (RT-PCR), sequences analysis, and phylogenetic analysis were performed for the pathogenic detection and analysis of these 326 clinical specimens. Results: Approximately 3.37% (11/326) of specimens tested positive for the CSFV by RT-PCR, which is lower than that of other regions of China. Sequence analysis of the partial E2 sequences of eleven CSFV strains showed that they shared 89.0-100.0% nucleotide (nt) and 95.0-100.0% amino acid (aa) homology, respectively. Phylogenetic analysis showed that these novel isolates belonged to the subgenotypes 2.1c and 2.1d, with subgenotype 2.1c being predominant. Conclusions: The CSFV was sporadic in China's Yunnan province from 2015 to 2021. Both 2.1c and 2.1d subgenotypes were found in this region, but 2.1c was dominant.

키워드

과제정보

This research was funded by National Key Research and Development Program of China (No. 2017YFD0501800) and Major Specialized Projects of Yunnan Science and Technology (No. 202102AE090007).

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