Journal of Biomedical Engineering Research (대한의용생체공학회:의공학회지)

The Korean Society of Medical and Biological Engineering (대한의용생체공학회)
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A Study on the Direction of Developing a Simulator for Performance Evaluation of Pulse Wave Detectors Through a Review of the Development Status of Cardiovascular Simulators

심혈관계 시뮬레이터 개발 동향 분석을 통한 맥파검사용기기 성능평가 시뮬레이터 연구개발 방향 모색

  • Lee, Ju-Yeon (Medical Device Research Division, National Institute of Food and Drug Safety Evaluation) ;
  • Kim, Jaeyoung (Medical Device Research Division, National Institute of Food and Drug Safety Evaluation) ;
  • Go, Dong-Hyun (Medical Device Research Division, National Institute of Food and Drug Safety Evaluation) ;
  • Lee, Ji-Won (Medical Device Research Division, National Institute of Food and Drug Safety Evaluation) ;
  • Lee, Tae-Hee (Medical Device Research Division, National Institute of Food and Drug Safety Evaluation) ;
  • Park, Chang-Won (Medical Device Research Division, National Institute of Food and Drug Safety Evaluation) ;
  • Lee, Su-Kyoung (Medical Device Research Division, National Institute of Food and Drug Safety Evaluation)
  • 이주연 (식품의약품안전평가원 의료제품연구부 의료기기연구과) ;
  • 김재영 (식품의약품안전평가원 의료제품연구부 의료기기연구과) ;
  • 고동현 (식품의약품안전평가원 의료제품연구부 의료기기연구과) ;
  • 이지원 (식품의약품안전평가원 의료제품연구부 의료기기연구과) ;
  • 이태희 (식품의약품안전평가원 의료제품연구부 의료기기연구과) ;
  • 박창원 (식품의약품안전평가원 의료제품연구부 의료기기연구과) ;
  • 이수경 (식품의약품안전평가원 의료제품연구부 의료기기연구과)
  • Received : 2022.03.24
  • Accepted : 2022.06.07
  • Published : 2022.06.30
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Abstract

In this study, it is intended to provide basic data that can help develop a cardiovascular simulator for performance evaluation of pulse wave detectors by identifying the development status of domestic and overseas cardiovascular simulators. A total of 119 papers were selected by excluding duplicate literature, gray literature, and literature not related to a cardiovascular simulator. Based on the selected literature, the research trend of cardiovascular simulators was analyzed. As a result of analyzing the purpose of the study, most of the simulators were developed to evaluate the hemodynamic properties of artificial hearts and valves. In addition, it was used for simulation evaluation or hemodynamic studies such as pulse wave studies. As a result of analyzing configurations of the simulators, a heart most often consisted of only one left ventricle. For blood vessels, the Windkessel model was most often constructed using chambers and valves. In most studies, blood was reproduced by mixing glycerin and water to reproduce both density and viscosity. In addition, as a result of analysis from the perspective of medical device performance evaluation, simulators for evaluating artificial heart and artificial valves have been studied a lot, whereas simulators for blood pressure, pulse wave, and blood flow devices have been relatively insignificant. Based on the review results, we suggested considerations when developing a simulator for performance evaluations of a pulse wave detector.

Keywords

Acknowledgement

본 연구는 2022년도 식품의약품안전처 연구개발비(21174심평연 225)로 수행되었으며 이에 감사드립니다.

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