Journal of Sasang Constitutional Medicine (사상체질의학회지)

The Society Of Sasang Constitutional Medicine (사상체질의학회)
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A Systematic Review on the Treatment of Post-Stroke Patients Based on Sasang Constitutional Medicine

사상의학적 중풍 후유증 치료에 대한 체계적 문헌 고찰

  • Oh, Hyunjoo (Dept. of Sasang Constitutional Medicine, Kyung Hee University Korean Medicine Hospital) ;
  • Lee, Jeongyun (Dept. of Sasang Constitutional Medicine, Div. of Clinical Medicine 4, School of Korean Medicine, Pusan National University) ;
  • Lee, Hyeri (Dept. of Sasang Constitutional Medicine, Kyung Hee University Korean Medicine Hospital) ;
  • Lee, Junhee (Dept. of Sasang Constitutional Medicine, College of Korean Medicine, Kyung Hee University)
  • 오현주 (경희대학교한방병원 사상체질과) ;
  • 이정윤 (부산대학교 한의학전문대학원 임상의학4교실 사상체질의학과) ;
  • 이혜리 (경희대학교한방병원 사상체질과) ;
  • 이준희 (경희대학교 한의과대학 사상체질과)
  • Received : 2022.06.14
  • Accepted : 2022.06.28
  • Published : 2022.06.30
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Abstract

Objectives The purpose of this study was to review and evaluate the clinical evidence of the efficacy and safety of treatment based on Sasang constitutional medicine (SCM) for post-stroke patients by systematic review and meta-analysis. Methods Randomized controlled trials (RCTs), published in 10 electronic databases up to December 2020, were searched. For the included studies, Cochrane's risk of bias assessment was performed to analyze the methodological quality. The strength of evidence was evaluated using the grading of recommendations assessment, development, and evaluation system based on the results of analyses. All review processes were performed by two independent researchers. Results Five RCTs were finally included. All included RCTs were conducted for one month on post-stroke patients in 60-80s, four studies on Tae-Eum patients and one study on So-Yang patients. Four types of constitution-specific herbal medicine (Chungpyesagan-tang, Cheongsimsanyak-tang, Yeoldahanso-tang, and Yangkyuksanhwa-tang) and constitution-specific acupuncture therapy were identified as interventions. More than half of the included studies were evaluated as low quality due to the high-risk of bias in selection, performance, and detection. The combination of constitution-specific herbal medicine, acupuncture, and conventional treatment was more effective in improving the patients' motor impairment, dysphagia, aphasia, and depression than conventional treatment alone. No serious adverse events by SCM treatment were reported. Conclusions SCM treatment may improve the sequelae of post-stroke patients safely in combination with conventional treatment. Since the quality of clinical evidence included in this study was low, higher quality clinical evidence obtained in well-designed clinical studies will be needed.

Keywords

Acknowledgement

본 연구는 보건복지부의 재원으로 한국보건산업진흥원의 보건의료기술연구개발사업 지원에 의하여 이루어진 것임(과제고유번호: HF20C0159).

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