Parasites, Hosts and Diseases

The Korea Society for Parasitology and Tropical Medicine (대한기생충학·열대의학회)
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Determination of Knockdown Resistance (kdr) Allele Frequencies (T929I mutation) in Head Louse Populations from Mexico, Canada, and Peru

  • Ponce-Garcia, Gustavo (Universidad Autonoma de Nuevo Leon, Facultad de Ciencias Biologicas, Laboratorio de Entomologia Medica) ;
  • Villanueva-Segura, Olga K. (Universidad Autonoma de Nuevo Leon, Facultad de Ciencias Biologicas, Laboratorio de Entomologia Medica) ;
  • Garza-Elizondo, Karina (Universidad Autonoma de Nuevo Leon, Facultad de Ciencias Biologicas, Laboratorio de Entomologia Medica) ;
  • Villegas-Ramirez, Heriberto M. (Universidad Autonoma de Nuevo Leon, Facultad de Ciencias Biologicas, Laboratorio de Entomologia Medica) ;
  • Fernandez-Salas, Ildefonso (Universidad Autonoma de Nuevo Leon, Facultad de Ciencias Biologicas, Laboratorio de Entomologia Medica) ;
  • Rodriguez-Sanchez, Iram P. (Universidad Autonoma de Nuevo Leon, Facultad de Ciencias Biologicas, Laboratorio de Entomologia Medica) ;
  • Dzul-Manzanilla, Felipe (Universidad Autonoma de Nuevo Leon, Facultad de Ciencias Biologicas, Laboratorio de Entomologia Medica) ;
  • Flores-Suarez, Adriana E. (Universidad Autonoma de Nuevo Leon, Facultad de Ciencias Biologicas, Laboratorio de Entomologia Medica)
  • Received : 2021.08.20
  • Accepted : 2022.04.26
  • Published : 2022.06.30
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Abstract

The head louse Pediculus humanus capitis (De Geer) is a hematophagous ectoparasite that inhabits the human scalp. The infestations are asymptomatic; however, skin irritation from scratching occasionally may cause secondary bacterial infections. The present study determined the presence and frequency of the knockdown resistance (kdr) mutation T929I in 245 head lice collected from Mexico, Peru, and Canada. Head lice were collected manually using a comb in the private head lice control clinic. Allele mutation at T9291 was present in 100% of the total sampled populations (245 lice) examined. In addition, 4.89% of the lice were homozygous susceptible, whereas 6.93% heterozygous and 88.16% homozygous were resistant, respectively. This represents the second report in Mexico and Quebec and fist in Lima.

Keywords

Acknowledgement

We thank Lizeth Rocha for her collaboration in this research work. We especially thank the principals, parents and children for their cooperation.

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