Journal of radiological science and technology (대한방사선기술학회지:방사선기술과학)

Korean Society of Radiological Science (대한방사선과학회)
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Comparison of Recovery Coefficients for Correction of Reduced SUV by Partial Volume Effect and Organ Movements in PET/CT Images

PET/CT 영상의 부분체적효과와 장기의 움직임으로 인해 감소된 SUV의 보정을 위한 회복계수의 비교

  • Kim, Youngjae (Department of Convergent Medical Physics, Graduate School of Engineering, Konkuk University) ;
  • Park, Hoon-Hee (Department of Radiological Technology, Shingu College) ;
  • Lee, Joo-Young (Department of Radiological Technology, Songho University) ;
  • So, Young (Department of Convergent Medical Physics, Graduate School of Engineering, Konkuk University) ;
  • Lee, Jeong-Woo (Department of Convergent Medical Physics, Graduate School of Engineering, Konkuk University)
  • 김영재 (건국대학교 산업대학원 의학물리융합학과) ;
  • 박훈희 (신구대학교 방사선과) ;
  • 이주영 (송호대학교 방사선과) ;
  • 소영 (건국대학교 산업대학원 의학물리융합학과) ;
  • 이정우 (건국대학교 산업대학원 의학물리융합학과)
  • Received : 2022.05.10
  • Accepted : 2022.06.08
  • Published : 2022.06.30
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Abstract

In this study, a recovery coefficient (RC) calculation was conducted that can correct the underestimation of the standardized uptake value (SUV) due to the partial volume effect (PVE) through phantom measurements and formulas. The experiment was conducted using a dynamic phantom capable of implement cranio-caudal movement at a respiratory rate of 15 times per minute along with the measured phantom experiment of the stopped state, and the RC of the moving state is calculated and compared. Ingenuity TF (Philips Healthcare, Netherland) was used as a positron emission tomography/computed tomography (PET/CT) device. PET-CT Phantom (Biodex Medical System, USA) was used as a phantom for measurement. A phantom image in a stationary state was acquired, and a moving phantom image was acquired using the AZ-733V Respiratory Phantom (Anzai Medical Co, Japan) capable of breathing movement in the cranio-caudal direction under the same acquisition parameters. For RC calculation, the sphere maximum radioactivity concentration and the background mean radioactivity concentration of the acquired images were measured, and the initially determined sphere and background radioactivity concentrations were calculated. The calculated RC was 0.08 to 0.72. The size of sphere smaller, it was confirmed that the RC reduced. And the RC in the moving state reduced than in the stationary state. As a result of this study, the change of the RC was confirmed according to the size of spheres and the phantom moving. Using the RC derived by implement movement of breathing with the respiratory phantom, it is possible to considering correction of underestimated SUV by the partial volume effect of PET images and the patient movements.

Keywords

Acknowledgement

This work was supported by the Korea Medical Device Development Fund grant funded by the Korea government (the Ministry of Science and ICT, the Ministry of Trade, Industry and Energy, the Ministry of Health & Welfare, the Ministry of Food and Drug Safety). (Project Number: 202012A01)

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