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Low-Dose Abdominal CT for Evaluating Suspected Appendicitis in Adolescents and Young Adults: Review of Evidence

  • Ji Hoon Park (Department of Radiology, Seoul National University Bundang Hospital) ;
  • Paulina Salminen (Department of Surgery, University of Turku) ;
  • Penampai Tannaphai (Department of Radiology, Faculty of Medicine, Ramathibodi Hospital, Mahidol University) ;
  • Kyoung Ho Lee (Department of Radiology, Seoul National University Bundang Hospital)
  • Received : 2021.07.22
  • Accepted : 2021.11.21
  • Published : 2022.05.01

Abstract

Due to its excellent diagnostic performance, CT is the mainstay of diagnostic test in adults with suspected acute appendicitis in many countries. Although debatable, extensive epidemiological studies have suggested that CT radiation is carcinogenic, at least in children and adolescents. Setting aside the debate over the carcinogenic risk of CT radiation, the value of judicious use of CT radiation cannot be overstated for the diagnosis of appendicitis, considering that appendicitis is a very common disease, and that the vast majority of patients with suspected acute appendicitis are adolescents and young adults with average life expectancies. Given the accumulated evidence justifying the use of low-dose CT (LDCT) of only 2 mSv, there is no reasonable basis to insist on using radiation dose of multi-purpose abdominal CT for the diagnosis of appendicitis, particularly in adolescents and young adults. Published data strongly suggest that LDCT is comparable to conventional dose CT in terms of clinical outcomes and diagnostic performance. In this narrative review, we will discuss such evidence for reducing CT radiation in adolescents and young adults with suspected appendicitis.

Keywords

Acknowledgement

The authors thank to Yousun Ko, Hae Young Kim, Jungheum Cho, Ji Ye Sim, and Seungjae Lee for help in preparing the manuscript.

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