Journal of the Korean Society of Radiology (대한영상의학회지)

The Korean Society of Radiology (대한영상의학회)
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Immunoglobulin G4-Related Disease Involving Various Head and Neck Regions: A Case Report

두경부에 국한된 표현형으로 발생한 면역글로불린 G4와 연관된 질환: 증례 보고

  • Jun Yong Im (Department of Radiology, Samsung Changwon Hospital, Sungkyunkwan University School of Medicine) ;
  • Miok Sunwoo (Department of Radiology, Samsung Changwon Hospital, Sungkyunkwan University School of Medicine)
  • 임준용 (성균관대학교 의과대학 삼성창원병원 영상의학과) ;
  • 선우미옥 (성균관대학교 의과대학 삼성창원병원 영상의학과)
  • Received : 2021.06.04
  • Accepted : 2021.09.24
  • Published : 2022.07.01
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Abstract

Immunoglobulin G4 (IgG4) related disease (IgG4-RD) is currently considered an immune-mediated condition and is recognized as a disorder group with common pathological, hematological, and clinical characteristics. This disease may involve diverse organs of the head and neck, and include mainly the lacrimal gland, orbit, thyroid gland, pituitary gland, and the meninges. Here, we report a case of IgG4-RD in a 65-year-old female showing head- and neck-limited but synchronously and mainly manifesting as otalgia and facial neuritis.

면역글로불린 G4 (immunoglobulin G4; 이하 IgG4) 관련 질병은 한때는 장기별 별개의 질환으로 진단되었던 질환들을 근래에 공통적인 병리학적, 혈액학적 및 임상적 특징을 가지는 면역 매개 질환을 일컫는다. 이 분류의 질환은 다양한 장기를 침범할 수 있으며, 두경부 역시 침범할 수 있다. 두경부를 침범하였을 경우, 주로 눈물샘, 안와, 갑상선, 뇌하수체 및 뇌수막 등을 주로 침범한다. 이에, 초기 급성중이염과 유양돌기염으로 증상으로 내원한 65세 여자환자에서 안면신경, 뇌경막, 비인강과 경부임파절에 동시에 발생하여 자기공명영상과 조직검사로 진단된 IgG4 연관 질환에 대하여 증례 보고를 하고자 한다.

Keywords

References

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