Journal of Korean Foot and Ankle Society (대한족부족관절학회지)

Korean Foot & Ankle Society (대한족부족관절학회)
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The Efficacy of Intra-Articular Hyaluronic Acid Injections in Ankle Osteoarthritis

족관절 골관절염에서의 관절 내 Hyaluronic Acid 주사의 유용성

  • Park, Chul Hyun (Department of Orthopaedic Surgery, College of Medicine, Yeungnam University) ;
  • Park, Jeong Jin (Department of Orthopaedic Surgery, Yeungnam University Medical Center) ;
  • Seok, Hyun Gyu (Department of Orthopaedic Surgery, Yeungnam University Medical Center) ;
  • Woo, In Ha (Department of Orthopaedic Surgery, Yeungnam University Medical Center)
  • 박철현 (영남대학교 의과대학 정형외과학교실) ;
  • 박정진 (영남대학교의료원 정형외과) ;
  • 석현규 (영남대학교의료원 정형외과) ;
  • 우인하 (영남대학교의료원 정형외과)
  • Received : 2022.02.14
  • Accepted : 2022.04.01
  • Published : 2022.06.15
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Abstract

Purpose: This study sought to investigate the appropriate indications for intra-articular injection of hyaluronic acid in ankle osteoarthritis, its efficacy at each stage of osteoarthritis and to compare the efficacy related differences at each stage. Materials and Methods: A retrospective study was conducted from January 2016 to September 2019 on 43 patients (50 cases) diagnosed with ankle arthritis and given intra-articular injection of hyaluronic acid. Patients were classified according to the modified Takakura ankle osteoarthritis stages. Stage 2 comprised 24 cases; stage 3A, 15 cases; stage 3B, 8 cases; and stage 4, 3 cases. The clinical evaluation was carried out using the visual analogue scale (VAS), American Orthopaedic Foot and Ankle Society (AOFAS) score, and the Foot and Ankle Outcome Score (FAOS). The patients' satisfaction with the injection was evaluated at 1 year after injection. A radiographic evaluation was performed to gauge the progression of osteoarthritis before and after the injection. Results: The VAS, AOFAS score, and FAOS at 3 months and 1 year after injection showed statistically significant improvements compared to those before the injection. There was a significant difference in the VAS for each stage over time; however, this was not the case with the AOFAS score and the FAOS. A significant improvement of the VAS after injection was seen only in stage 3A when compared with the other stages. The overall satisfaction rate with the injection was 90%. There were no ankle osteoarthritic stage changes in the serial follow-up radiograph. Conclusion: Intra-articular injection of hyaluronic acid resulted in a significant clinical improvement up to 1 year after the injection. Therefore, the intra-articular injection of hyaluronic acid could be a treatment option for ankle osteoarthritis.

Keywords

References

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