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Estimation of Utility Weights for Prostate-related Health States in Korea

  • Kim, Seon-Ha (Department of Nursing, Dankook University) ;
  • Ock, Minsu (Department of Preventive Medicine, Ulsan University Hospital, University of Ulsan College of Medicine) ;
  • Jo, Min-Woo (Department of Preventive Medicine, University of Ulsan College of Medicine) ;
  • Park, Sungchan (Department of Urology, Ulsan University Hospital, University of Ulsan College of Medicine)
  • Received : 2021.07.29
  • Accepted : 2021.12.10
  • Published : 2022.05.31

Abstract

Objectives: Very limited previous research has investigated the utility weights of prostate-related diseases in the general population in Korea. The purpose of this study was to calculate the utility of prostate-related health states in the Korean general public using the standard gamble (SG) method. Methods: Seven health states for hypothetical prostate cancers, 1 for benign prostate hyperplasia, and 1 for erectile dysfunction were developed based on patient education material and previous publications. In total, 460 responses from the Korean general population were used to analyze the utility of prostate-related health states. Computer-assisted personal interviews were conducted, and utility values were measured using a visual analogue scale (VAS) and SG. Mean utility values were calculated for each prostate-related health state. Results: The mean utility values of prostate cancer derived from SG ranged from 0.281 (metastatic castration-refractory prostate cancer) to 0.779 (localized prostate cancer requiring prostatectomy). The utility value of benign prostate hyperplasia was 0.871, and that of erectile dysfunction was 0.812. The utility values obtained using the SG method in all conditions were higher than the values obtained by VAS. There were no significant demographic variables affecting utility values in multivariate analysis. Conclusions: Our findings might be useful for economic evaluation and utility calculation of screening and interventions for prostate-related conditions in the general population.

Keywords

Acknowledgement

This study was supported by a grant from the National R & D Program for Cancer Control, Ministry of Health and Welfare, Republic of Korea (No. 1520140).

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