Journal of Chest Surgery

The Korean Society for Thoracic and Cardiovascular Surgery (대한심장혈관흉부외과학회)
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A Case Report of Resection of a Mediastinal Paraganglioma: Why All the Fuss?

  • Staunton, Laura Mary (Department of Cardiothoracic Surgery, St. James's Hospital) ;
  • Casey, Laura (Department of Cardiothoracic Surgery, St. James's Hospital) ;
  • Young, Vincent K. (Department of Cardiothoracic Surgery, St. James's Hospital) ;
  • Fitzmaurice, Gerard J. (Department of Cardiothoracic Surgery, St. James's Hospital)
  • Received : 2021.09.29
  • Accepted : 2021.11.17
  • Published : 2022.04.05
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Abstract

Mediastinal paragangliomas are rare tumors that have only been reported in individual cases or limited case series. Surgical resection of these tumors can be challenging, as they are highly vascular and intimately related to the great vessels. Surgery is usually performed via median sternotomy with or without cardiopulmonary bypass. We present the case of a mediastinal paraganglioma that was resected via a left-sided posterolateral thoracotomy. Histopathology revealed a completely resected 38-mm paraganglioma with a positive station 5 lymph node, indicative of locally aggressive disease. Hereditary paragangliomas are associated with malignant transformation; therefore, genetic testing is important. These tumors do not respond well to chemoradiotherapy, and consequently lifelong surveillance for early detection of recurrence is recommended.

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References

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