Journal of the Korea Convergence Society (한국융합학회논문지)

Korea Convergence Society (한국융합학회)
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Antibacterial effect of natural extracts on oral microorganisms

천연추출물이 구강미생물에 미치는 항균 효과

  • 황혜정 (건양사이버대학교 보건의료복지학과) ;
  • 김민영 (호원대학교 치위생학과) ;
  • 강경희 (건양대학교 치위생학과)
  • Received : 2022.03.31
  • Accepted : 2022.05.20
  • Published : 2022.05.28
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Abstract

In this study, the antibacterial effect of silkworm extract and Momordica charantia extract on S. mutans and F. nucleatum was investigated. S. mutans or F. nucleatum and 0%, 2%, 4%, 8% concentration of silkworm powder or Momordica charantia powder extract were added to the BHI liquid medium and cultured, and the sample was measured at an optical density of 600nm. As a result, S. mutans, the absorbance value was significantly decreased only in 8% of the silkworm extract, and the absorbance value was significantly decreased in all concentrations in the Momordica charantia extract. The absorbance of F. nucleatum was significantly decreased in a concentration-dependent manner in both the silkworm extract and the Momordica charantia extract. This suggests the possibility that silkworm extract and Momordica charantia extract can be used as materials for the prevention and treatment of oral diseases.

본 연구에서는 누에 추출물과 여주 추출물이 S. mutans와 F. nucleatum에 미치는 항균효과를 알아보고자 하였다. BHI 액체배지에 S. mutans 또는 F. nucleatum과 0%, 2%, 4%, 8% 농도의 누에가루 또는 여주가루 추출물을 첨가하여 배양한 뒤 광학밀도 600nm에서 시료를 측정하였다, 그 결과 S. mutans의 흡광도는 누에 추출물에서는 8%에서만 유의적으로 흡광도의 수치가 감소하였고 여주 추출물에서는 모든 농도에서 유의적으로 흡광도의 수치가 감소하였다. F. nucleatum의 흡광도는 누에 추출물과 여주 추출물에 모두 농도 의존적으로 유의적으로 감소하였다. 이는 누에 추출물과 여주 추출물이 구강질병의 예방 및 치료들 위한 소재로 사용 할 수 있는 가능성을 시사한다.

Keywords

Acknowledgement

This work was supported by the National Research Foundation of Korea (NRF) grant funded by the Korea government (Ministry of Education) (NRF-2017R1D1A1B03035544).

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