DOI QR코드

DOI QR Code

Modified high-flow nasal cannula for children with respiratory distress

  • Itdhiamornkulchai, Sarocha (Division of Pediatric Critical Care Medicine, Department of Pediatrics, Faculty of Medicine, Ramathibodi Hospital, Mahidol University) ;
  • Preutthipan, Aroonwan (Division of Pediatric Pulmonology, Department of Pediatrics, Faculty of Medicine, Ramathibodi Hospital, Mahidol University) ;
  • Vaewpanich, Jarin (Division of Pediatric Critical Care Medicine, Department of Pediatrics, Faculty of Medicine, Ramathibodi Hospital, Mahidol University) ;
  • Anantasit, Nattachai (Division of Pediatric Critical Care Medicine, Department of Pediatrics, Faculty of Medicine, Ramathibodi Hospital, Mahidol University)
  • 투고 : 2020.08.14
  • 심사 : 2021.05.13
  • 발행 : 2022.03.15

초록

Background: High-flow nasal cannula (HFNC) is a noninvasive respiratory support that provides the optimum flow of an air-oxygen mixture. Several studies demonstrated its usefulness and good safety profile for treating pediatric respiratory distress patients. However, the cost of the commercial HFNC is high; therefore, the modified high-flow nasal cannula was developed. Purpose: This study aimed to compare the effectiveness, safety, and nurses' satisfaction of the modified system versus the standard commercial HFNC. Methods: This prospective comparative study was performed in a tertiary care hospital. We recruited children aged 1 month to 5 years who developed acute respiratory distress and were admitted to the pediatric intensive care unit. Patients were assigned to 2 groups (modified vs. commercial). The effectiveness and safety assessments included vital signs, respiratory scores, intubation rate, adverse events, and nurses' satisfaction. Results: A total of 74 patients were treated with HFNC. Thirtynine patients were assigned to the modified group, while the remaining 35 patients were in the commercial group. Intubation rate and adverse events did not differ significantly between the 2 groups. However, the commercial group had higher nurses' satisfaction scores than the modified group. Conclusion: Our findings suggest that our low-cost modified HFNC could be a useful respiratory support option for younger children with acute respiratory distress, especially in hospital settings with financial constraints.

키워드

과제정보

The authors would like to acknowledge all colleagues in Pediatric Critical Care and Pulmonary Division, the Department of Pediatrics Ramathibodi Hospital, Mahidol University. We would also like to thank Prof. Pat Mahachoklertwattana for the critical review of the article and Dr. Jeeraparn Phosuwattanakul for drawing the modified high-flow nasal cannula picture. We would like to thank Mr. Stephen Pinder for grammar correction. Furthermore, our special thanks to all patients who participated in this study.

참고문헌

  1. Ward JJ. High-flow oxygen administration by nasal cannula for adult and perinatal patients. Respir Care 2013;58:98-122. https://doi.org/10.4187/respcare.01941
  2. Dysart K, Miller TL, Wolfson MR, Shaffer TH. Research in high flow therapy: mechanisms of action. Respir Med 2009;103:1400-5. https://doi.org/10.1016/j.rmed.2009.04.007
  3. Bressan S, Balzani M, Krauss B, Pettenazzo A, Zanconato S, Baraldi E. High-flow nasal cannula oxygen for bronchiolitis in a pediatric ward: a pilot study. Eur J Pediatr 2013;172:1649-56. https://doi.org/10.1007/s00431-013-2094-4
  4. Bueno Campana M, Olivares Ortiz J, Notario Munoz C, Ruperez Lucas M, Fernandez Rincon A, Patino Hernandez O, et al. High flow therapy versus hypertonic saline in bronchiolitis: randomised controlled trial. Arch Dis Child 2014;99:511-5. https://doi.org/10.1136/archdischild-2013-305443
  5. Mikalsen IB, Davis P, Oymar K. High flow nasal cannula in children: a literature review. Scand J Trauma Resusc Emerg Med 2016;24:93. https://doi.org/10.1186/s13049-016-0278-4
  6. Kwon JW. High-flow nasal cannula oxygen therapy in children: a clinical review. Clin Exp Pediatr 2020;63:3-7. https://doi.org/10.3345/kjp.2019.00626
  7. Ten Brink F, Duke T, Evans J. High-flow nasal prong oxygen therapy or nasopharyngeal continuous positive airway pressure for children with moderate-to-severe respiratory distress?*. Pediatr Crit Care Med 2013;14:e326-31. https://doi.org/10.1097/PCC.0b013e31828a894d
  8. Hutchings FA, Hilliard TN, Davis PJ. Heated humidified high-flow nasal cannula therapy in children. Arch Dis Child 2015;100:571-5. https://doi.org/10.1136/archdischild-2014-306590
  9. Kawaguchi A, Yasui Y, deCaen A, Garros D. The clinical impact of heated humidified high-flow nasal cannula on pediatric respiratory distress. Pediatr Crit Care Med 2017;18:112-29. https://doi.org/10.1097/PCC.0000000000000985
  10. Franklin D, Babl FE, Schlapbach LJ, Oakley E, Craig S, Neutze J, et al. A randomized trial of high-flow oxygen therapy in infants with bronchiolitis. N Engl J Med 2018;378:1121-31. https://doi.org/10.1056/NEJMoa1714855
  11. Hegde S, Prodhan P. Serious air leak syndrome complicating high-flow nasal cannula therapy: a report of 3 cases. Pediatrics 2013;131:e939-44. https://doi.org/10.1542/peds.2011-3767
  12. Vareesunthorn I, Preutthipan A. Modified high-flow nasal cannula in young children with pneumonia: a 3-year retrospective study. Pediatr Respirol Crit Care Med 2018;2:45-50. https://doi.org/10.4103/prcm.prcm_2_18
  13. Kaya Z, Turktas I. Correlation of clinical score to pulmonary function and oxygen saturation in children with asthma attack. Allergol Immunopathol 2007;35:169-73. https://doi.org/10.1157/13110310
  14. Liu LL, Gallaher MM, Davis RL, Rutter CM, Lewis TC, Marcuse EK. Use of a respiratory clinical score among different providers. Pediatr Pulmonol 2004;37:243-8.
  15. Riese J, Fierce J, Riese A, Alverson BK. Effect of a hospital-wide high-flow nasal cannula protocol on clinical outcomes and resource utilization of bronchiolitis patients admitted to the PICU. Hosp Pediatr 2015;5:613-8. https://doi.org/10.1542/hpeds.2014-0220
  16. Malhotra D, Gurcoo S, Qazi S, Gupta S. Randomized comparative efficacy of dexamethasone to prevent postextubation upper airway complications in children and adults in ICU. Indian J Anaesth 2009;53:442-9.
  17. Arora B, Mahajan P, Zidan MA, Sethuraman U. Nasopharyngeal airway pressures in bronchiolitis patients treated with high-flow nasal cannula oxygen therapy. Pediatr Emer Care 2012;28:1179-84. https://doi.org/10.1097/PEC.0b013e318271a671
  18. Schibler A, Pham TM, Dunster KR, Foster K, Barlow A, Gibbons K, et al. Reduced intubation rates for infants after introduction of high-flow nasal prong oxygen delivery. Intensive Care Med 2011;37:847-52. https://doi.org/10.1007/s00134-011-2177-5
  19. McKiernan C, Chua LC, Visintainer PF, Allen H. High flow nasal cannulae therapy in infants with bronchiolitis. J Pediatr 2010;156:634-8. https://doi.org/10.1016/j.jpeds.2009.10.039
  20. Wraight TI, Ganu SS. High-flow nasal cannula use in a paediatric intensive care unit over 3 years. Crit Care Resusc 2015;17:197-201.
  21. Long E, Babl FE, Duke T. Is there a role for humidified heated high-flow nasal cannula therapy in paediatric emergency departments? Emerg Med J 2016;33:386-9. https://doi.org/10.1136/emermed-2015-204914